The Late Show with David Letterman
Premiere Date: August 30, 1993
Genres:
Casts:
David Letterman, Paul Shaffer, Alan Kalter, Bill Wendell
Air Time:
11:35pm
Country:
US
Air Day:
Thursday
Labels:
The Late Show with David Letterman is an hour-long weeknight comedy and talk-show broadcast by CBS from the Ed Sullivan Theater on Broadway in New York City.
Late Show with David Letterman is an American late-night talk show hosted by David Letterman on CBS. The show debuted on August 30, 1993, and is produced by Letterman's production company, Worldwide Pants Incorporated and CBS Television Studios. The show's music director and band-leader of the house band, the CBS Orchestra, is Paul Shaffer. The head writer is Matt Roberts and the announcer is Alan Kalter. Of the major U.S. late-night programs, Late Show ranks second in cumulative average viewers over time and third in number of episodes over time. The show leads other late night shows in ad revenue with $271 million in 2009.
In most U.S. markets the show airs at 11:35 p.m. Eastern/Pacific time, but is recorded Monday through Wednesday at 4:30 p.m., and Thursdays at 3:30 p.m and 6:00 p.m. The second Thursday episode usually airs on Friday of that week.
In 2002, Late Show with David Letterman was ranked No. 7 on TV Guide's 50 Greatest TV Shows of All Time. CBS has a contract with Worldwide Pants to continue the show through 2014; by then, Letterman will surpass Johnny Carson as the longest tenured late-night talk show host.. Watch TV shows online free. Watch The Late Show with David Letterman series online.
Seasons
Season 22 Episodes
- Episode 1 : Bill Murray, Tom Brokaw, Paul Newman, Billy Joel
- Episode 2 : Robin Williams, John Mellencamp, Jonathan Estrata
- Episode 3 : Demi Moore, Bev Tanner, Spin Doctors
- Episode 4 : Martin Short, Cyndi Lauper
- Episode 5 : Debra Winger, Soul Asylum
- Episode 6 : Richard Lewis, Shawn Bouroughs, Midnight Oil
- Episode 7 : Michael J. Fox, Rosie Perez
- Episode 8 : Al Gore, Kim Basinger, Chris Isaak
- Episode 9 : Ellen Barkin, Chris Mad Dog Russo, Lenny Kravitz
- Episode 10 : Siskel & Ebert, Robert Plant
- Episode 11 : Bruce Willis, Steven Wright
- Episode 12 : Paul Reiser, Mike Ditka, John Hiatt
- Episode 13 : Jeff Goldblum, Louie Anderson, Jerry Garcia & David Grisman
- Episode 14 : Bonnie Hunt, Latrisha Baldrick, Patti Smyth
- Episode 15 : Super Dave Osborne, Laura Dern, Stone Temple Pilots
- Episode 16 : Sarah Jessica Parker, Jim Abbot, Patty Scialfa
- Episode 17 : Robert Urich, Ellen Degeneres, Tim Tomasic
- Episode 18 : Tony Randall, Elizabeth Perkins, Aaron Neville
- Episode 19 : Mike Myers, John Kruk, Belinda Carlisle
- Episode 20 : Glenn Close, James Taylor
- Episode 21 : Matthew Broderick, Julie Krone, Neil Diamond
- Episode 22 : Jimmy Carter, Brett Butler, Daniel Boulud
- Episode 23 : Jerry Lewis, Sparky Mortimer, Rod Stewart
- Episode 24 : Lily Tomlin, Adam Sandler, Mike Lupica
- Episode 25 : Andie MacDowell, Graham Parker, Bill Scheft
- Episode 26 : Sylvester Stallone, Melissa Etheridge, Janeane Garofalo
- Episode 27 : Isabella Rossellini, Bob Saget, Johnny Cash
- Episode 28 : Candice Bergen, John Mendoza
- Episode 29 : Don Rickles, Tracey Ullman, Johnny Cash
- Episode 30 : Connie Chung, Mary Chapin Carpenter
- Episode 31 : Kathie Lee Gifford, Matt Dillon
- Episode 32 : Stupid Pet Tricks, Howard Stern, Rosanne Cash
- Episode 33 : Kirstie Alley, Rick Ocasek, Jeff Colton
- Episode 34 : David Brenner, Gloria Estefan, Sean Young
- Episode 35 : Tom Arnold, Rich Hall, Jon Weiss
- Episode 36 : Dennis Miller, Tony Bennett, Sandra Bullock
- Episode 37 : David Steinberg, Emmylou Harris, Bo Jackson
- Episode 38 : Dan Rather, Penelope Ann Miller, Gin Blossoms
- Episode 39 : Bob Newhart, Guru, Chloe Disker
- Episode 40 : Martin Mull, The Pogues, Jean Louie
- Episode 41 : Sean Connery, Jake Johannsen, Fran Drescher
- Episode 42 : Phil Donahue, Art Garfunkel, Lenny Dykstra, Paul Molitor
- Episode 43 : Marv Albert, Cindy Crawford, Natalie Cole
- Episode 44 : George Foreman, INXS & Ray Charles
- Episode 45 : Martin Lawrence, Phil Collins
- Episode 46 : Jay Thomas, Squeeze, Martha Stewart
- Episode 47 : Terry Garr, Paul Simon
- Episode 48 : Mike Wallace, Jimmy Cliff, Faith Ford
- Episode 49 : Annie Potts, Natalie Merchant, Dorothy Nash
- Episode 50 : Tony Curtis, The Breeders, Calvin Trillian
- Episode 51 : Michael Keaton, Barbara Walters
- Episode 52 : Evander Holyfield, Phil Hartman, The BoDeans
- Episode 53 : Mary Tyler Moore, Jackson Browne, Rita Rudner
- Episode 54 : Tom Selleck, Pete Townsend
- Episode 55 : Barry Bonds, Carol Kane, Living Colour
- Episode 56 : Sinbad, Trisha Yearwood, Charlie Sheen
- Episode 57 : Billy Crystal, Los Lobos
- Episode 58 : Stupid Human Tricks, Jon Lovitz, George Thoroughgood
- Episode 59 : Billy Connolly, Bob Dylan, Charles Kuralt
- Episode 60 : Dana Carvey, Meatloaf, Joan Cusak
- Episode 61 : Marilu Henner, Heart, Father Guido Sarducci
- Episode 62 : Robert Klein, Cowboy Junkies, Bobby Knight
- Episode 63 : Bryant Gumbel, Taylor Dayne, Dave Attel
- Episode 64 : Penn & Teller, Dwight Yoakam, Gabriel Byrne
- Episode 65 : Kelsey Grammar, Patrick Ewing, Warren Zevon
- Episode 66 : James Belushi, Carlene Carter, Lauren Holley
- Episode 67 : Robin Williams, Larry Johnson
- Episode 68 : Sam Donaldson, Mike Myers, Nanci Griffith
- Episode 69 : Jeremy Irons, Bruce Hornsby
- Episode 70 : Charles Grodin, Bryan Adams, Jack Hannah
- Episode 71 : Sally Field, Carly Simon, Robert Duvall
- Episode 72 : Larry King, The Band, Kevin Pollack
- Episode 73 : Luciano Pavarotti, Marisa Tomei, Wayne Cotter
- Episode 74 : Tom Hanks, Gipsy Kings, Joan Plowright
- Episode 75 : Rush Limbaugh, Harry Connick Jr.
- Episode 76 : Whoopi Goldberg, Clint Black, John Witherspoon
- Episode 77 : Will Smith, The Lemonheads, Emmit Smith
- Episode 78 : Bob Costas, Toni Braxton, Debi Mazar
- Episode 79 : Dennis Franz, Mike Judge, Andy Williams
- Episode 80 : Joan Lunden, Ian Moore, Wendy Wasserstein
- Episode 81 : Jason Priestly, Terry Bradshaw, Norm MacDonald
- Episode 82 : Bonnie Hunt, Tony Toni Tone, Dennis Rogers
- Episode 83 : Julia Roberts, Cracker, Wolfgang Puck
- Episode 84 : Rosanne and Tom Arnold, Jon Bon Jovi
- Episode 85 : Jane Pauley, Art Donavan
- Episode 86 : Beau Bridges, Sandra Bernhard, 4 Non Blondes
- Episode 87 : Rosie O'Donnell, Lou Reed, Neil Patrick Harris
- Episode 88 : Chris Elliot, Itzhak Perlman, Cokie Roberts
- Episode 89 : Martin Mull, Drew Carey, Dana Delaney
- Episode 90 : Rudolph Giuliani, Faith Hill, Ricki Lake
- Episode 91 : Troy Aikman, Marilyn Horne, Jon Stewart
- Episode 92 : Smothers Brothers, Indigo Girls, Sara McClendan
- Episode 93 : George Carlin, Urge Overkill, Jan Hooks
- Episode 94 : Chevy Chase, George Miller, Halle Berry
- Episode 95 : Richard Harris, Taj Mahal & Etta James, David Spade
- Episode 96 : David Brenner, Travis Tritt, Madeline Stowe
- Episode 97 : Kathie Lee Gifford, Aaron Neville, Bruno Kirby
- Episode 98 : Demi Moore, Willie Nelson & Shelby Lynne, Al Franken
- Episode 99 : Dan Rather, Dave Pirner & Victoria Williams, Brett Hull
- Episode 100 : Jimmy Johnson, Martin Lawrence, Concrete Blonde
- Episode 101 : Show #0220
- Episode 102 : Show #0221
- Episode 103 : Show #0222
- Episode 104 : Show #0223
- Episode 105 : Show #0224
- Episode 106 : Show #0225
- Episode 107 : Show #0226
- Episode 108 : Show #0227
- Episode 109 : Show #0228
- Episode 110 : Show #0229
- Episode 111 : Show #0230
- Episode 112 : Show #0231
- Episode 113 : Show #0232
- Episode 114 : Show #0233
- Episode 115 : Show #0234
- Episode 116 : Show #0235
- Episode 117 : Show #0236
- Episode 118 : Show #0237
- Episode 119 : Show #0238
- Episode 120 : Show #0239
- Episode 121 : Show #0240
- Episode 122 : Show #0241
- Episode 123 : Show #0242
- Episode 124 : Show #0243
- Episode 125 : Show #0244
- Episode 126 : Show #0245
- Episode 127 : Show #0246
- Episode 128 : Show #0247
- Episode 129 : Show #0248
- Episode 130 : Show #0249
- Episode 131 : Show #0250
- Episode 132 : Show #0251
- Episode 133 : Show #0252
- Episode 134 : Show #0253
- Episode 135 : Show #0254
- Episode 136 : Show #0255
- Episode 137 : Show #0256
- Episode 138 : Show #0257
- Episode 139 : Show #0258
- Episode 140 : Show #0259
- Episode 141 : Show #0260
- Episode 142 : Show #0261
- Episode 143 : Show #0262
- Episode 144 : Show #0263
- Episode 145 : Show #0264
- Episode 146 : Show #0265
- Episode 147 : Show #0266
- Episode 148 : Show #0267
- Episode 149 : Show #0268
- Episode 150 : Show #0269
- Episode 151 : Show #0270
- Episode 152 : Show #0271
- Episode 153 : Show #0272
- Episode 154 : Show #0273
- Episode 155 : Show #0274
- Episode 156 : Show #0275
- Episode 157 : Show #0276
- Episode 158 : Show #0277
- Episode 159 : Show #0278
- Episode 160 : Show #0279
- Episode 161 : Show #0280
- Episode 162 : Show #0281
- Episode 163 : Show #0282
- Episode 164 : Show #0283
- Episode 165 : Show #0284
- Episode 166 : Show #0285
- Episode 167 : Show #0286
- Episode 168 : Show #0287
- Episode 169 : Show #0288
- Episode 170 : Show #0289
- Episode 171 : Show #0290
- Episode 172 : Show #0291
- Episode 173 : Show #0292
- Episode 174 : Show #0293
- Episode 175 : Show #0294
- Episode 176 : Show #0295
- Episode 177 : Show #0296
- Episode 178 : Show #0297
- Episode 179 : Show #0298
- Episode 180 : Show #0299
- Episode 181 : Show #0300
- Episode 182 : Show #0301
- Episode 183 : Show #0302
- Episode 184 : Show #0303
- Episode 185 : Show #0304
- Episode 186 : Show #0305
- Episode 187 : Show #0306
- Episode 188 : Show #0307
- Episode 189 : Show #0308
- Episode 190 : Show #0309
- Episode 191 : Show #0310
- Episode 192 : Show #0311
- Episode 193 : Show #0312
- Episode 194 : Show #0313
- Episode 195 : Show #0314
- Episode 196 : Show #0315
- Episode 197 : Show #0316
- Episode 198 : Show #0317
- Episode 199 : Show #0318
- Episode 200 : Show #0319
- Episode 201 : Show #0440
- Episode 202 : Show #0441
- Episode 203 : Show #0442
- Episode 204 : Show #0443
- Episode 205 : Show #0444
- Episode 206 : Show #0445
- Episode 207 : Show #0446
- Episode 208 : Show #0447
- Episode 209 : Show #0448
- Episode 210 : Show #0449
- Episode 211 : Show #0450
- Episode 212 : Show #0451
- Episode 213 : Show #0452
- Episode 214 : Show #0453
- Episode 215 : Show #0454
- Episode 216 : Show #0455
- Episode 217 : Show #0456
- Episode 218 : Show #0457
- Episode 219 : Show #0458
- Episode 120 : Show #0459
- Episode 121 : Show #0460
- Episode 122 : Show #0461
- Episode 123 : Show #0462
- Episode 124 : Show #0463
- Episode 125 : Show #0464
- Episode 126 : Show #0465
- Episode 127 : Show #0466
- Episode 128 : Show #0467
- Episode 129 : Show #0468
- Episode 130 : Show #0469
- Episode 131 : Show #0470
- Episode 132 : Show #0471
- Episode 133 : Show #0472
- Episode 134 : Show #0473
- Episode 135 : Show #0474
- Episode 136 : Show #0475
- Episode 137 : Show #0476
- Episode 138 : Show #0477
- Episode 139 : Show #0478
- Episode 140 : Show #0479
- Episode 141 : Show #0480
- Episode 142 : Show #0481
- Episode 143 : Show #0482
- Episode 144 : Show #0483
- Episode 145 : Show #0484
- Episode 146 : Show #0485
- Episode 147 : Show #0486
- Episode 148 : Show #0487
- Episode 149 : Show #0488
- Episode 150 : Show #0489
- Episode 151 : Show #0490
- Episode 152 : Show #0491
- Episode 153 : Show #0492
- Episode 154 : Show #0493
- Episode 155 : Show #0494
- Episode 156 : Show #0495
- Episode 157 : Show #0496
- Episode 158 : Show #0497
- Episode 159 : Show #0498
- Episode 160 : Show #0499
- Episode 161 : Bob Hoskins, Martha Stewart, Al Green
- Episode 162 : Jean Claude Van Damme, Kirstin Dunst, Michael Bolton
- Episode 163 : Martin Short, Bev Tanner, The Dave Matthews Band
- Episode 164 : Harrison Ford, Bonnie Hunt, Bruce Springsteen
- Episode 165 : Greg Kinnear, Janeane Garofalo, White Zombie
- Episode 166 : Kathie Lee Gifford, Aaron Neville
- Episode 167 : Jack Lemmon, Natalie Merchant
- Episode 168 : Howard Stern, Melissa Etheridge
- Episode 169 : Geena Davis, Goo Goo Dolls
- Episode 170 : Rosie O'Donnell, Mike Judge, Darlene Love
- Episode 171 : Stupid Human Tricks, Julianna Marguiles, Del Amitri
- Episode 172 : Mandy Patinkin, Terry Gilliam
- Episode 173 : Robin Williams, Lauren Hutton, Chris Isaak
- Episode 174 : Susan Sarandon, Drew Carey
- Episode 175 : Lisa Kudrow, Art Donovan, Blues Traveler
- Episode 176 : Chevy Chase, Marv Albert, Bruce Hornsby
- Episode 177 : Tom Brokaw, Greg Fitzsimmons, Faith Hill
- Episode 178 : Denis Leary, Bridget Hall, Toad the Wet Sprocket
- Episode 179 : Sam Neill, Itzhak Perlman
- Episode 180 : Pauly Shore, Ashley Judd
- Episode 181 : Sandra Bullock, Marlon Wayans, Laurence Tai
- Episode 182 : Jason Alexander, Elisabeth Shue
- Episode 183 : Tim Robbins, Justin Wilson, Martina McBride, Norm MacDonald
- Episode 184 : David Brenner, B.B. King
- Episode 185 : Mia Farrow, Martin Scorcese, Brandy
- Episode 186 : Don Rickles, Mary Stuart Masterson, Joe Ely & Todd Snider
- Episode 187 : Matt Dillon, Reggie Miller, Pam Tillis
- Episode 188 : Conan O'Brian, Mira Sorvino, Seven Mary Three
- Episode 189 : Richard Simmons, Christine Lahti, Nanci Griffith & the Crickets
- Episode 190 : Jay Thomas, Larry Miller
- Episode 191 : Elle MacPherson, David Spade, D'Angelo
- Episode 192 : Alec Baldwin, Dwight Yoakam, Natalie Portman
- Episode 193 : Cybill Sheperd, Al Franken, Sati Achath
- Episode 194 : Jack Hanna, Tammy Faye Messner, Aimee Mann
- Episode 195 : Joan Collins, Robert Downey Jr., Jean Louisa Kelly
- Episode 196 : Chuck Norris, Samantha Mathis
- Episode 197 : Stupid Pet Tricks, Ray Liotta, Soul Asylum
- Episode 198 : Uma Thurman, Norm MacDonald, Ramones
- Episode 199 : Chris Farley, Gin Blossoms, Joe & Mary Graziano
- Episode 200 : Adam Sandler, Jackie Chan, Red Hot Chili Peppers
- Episode 201 : Chuck Norris, Anthony Clark, Jewel
- Episode 202 : Mira Sorvino, Vincent Perez, Beck
- Episode 203 : Whoopi Goldberg, Al Franken, Colonel Ron Severson
- Episode 204 : Adam Sandler, David Cone, LeAnn Rimes
- Episode 205 : Bill Cosby, Brian Williams, No Doubt
- Episode 206 : Jamie Lee Curtis, Pete Sampras, John Mellencamp
- Episode 207 : Jon Stewart, Marv Albert, Cranberries
- Episode 208 : Cybill Sheperd, Carl Coccilone, Ray Romano
- Episode 209 : Tom Brokaw, Natasha Henstridge, Fan Yang
- Episode 210 : John McEnroe, Illeana Douglas, 311
- Episode 211 : Tim Allen, Tyson Koenig, Suzanne Vega
- Episode 212 : Fran Drescher, Jesse Jackson, Travis Tritt
- Episode 213 : Bill Cosby, Kin-Jin Mark, A Tribe Called Quest
- Episode 214 : Goldie Hawn, Louie C.K.
- Episode 215 : Stupid Pet Tricks, Drew Barrymore, Tony Avena, Pearl Jam
- Episode 216 : Sarah Jessica Parker, Andy Richter, Darrell Hammond
- Episode 217 : Ellen DeGeneres, Stephen King, Trisha Yearwood
- Episode 218 : William Baldwin, Jeff Gordon, Vince Gill
- Episode 219 : Hugh Grant, Elizabeth Berkley, Donna Lewis
- Episode 220 : Kirstie Alley, Matthew Broderick
- Episode 121 : Ricki Lake, Gillian Anderson, Tom Petty & the Heartbreakers
- Episode 122 : Tom Hanks, Gina Gershon, Riverdance
- Episode 123 : Val Kilmer, Nicole Sullivan, ZZ Top
- Episode 124 : Julie Andrews, Pee Wee Scheidt, Dave Matthews Band
- Episode 125 : Wayne Gretzky, Jonathan Silverman, Tori Amos
- Episode 126 : Michael J. Fox, Jeanne Moreau, Ray Davies
- Episode 127 : Sam Donaldson, Spike Lee, Clint Black
- Episode 128 : Samuel L. Jackson, Leela Rashon, Midnight Oil
- Episode 129 : Geena Davis, Peter Gallagher, Andy Kindler
- Episode 130 : George Foreman, Tom Everett Scott, Shawn Colvin
- Episode 131 : Cindy Crawford, Jack Hanna, Lyle Lovett
- Episode 132 : Rosie O'Donnell, Jon Favreau, Sheryl Crow
- Episode 133 : Jon Lovitz, Ken Olin, Enrique Iglesias
- Episode 134 : Ted Danson, Claire Danes, Phil Collins
- Episode 135 : Jimmy Smits, John Leguizamo, Brian Regan
- Episode 136 : Joe Torre, Don Rickles, The Heads
- Episode 137 : George Steinbrenner, Jeremy Piven, Chris Isaak
- Episode 138 : Isabella Rossellini, Garry Marshall, Bryn Terfel
- Episode 139 : Jeff Foxworthy, Naomi Campbell, Jake Johannsen
- Episode 140 : Stupid Human Tricks, Dana Carvey, Steven Wright
- Episode 141 : Mel Gibson, Christine Lahti, Joni Mitchell
- Episode 142 : Marisa Tomei, James Carville, John Michael Montgomery
- Episode 143 : Brett Butler, Gary Sinise, Bob McCoy
- Episode 144 : Bob Dole, Ted Koppel, Mary Chapin Carpenter
- Episode 145 : Jeff Bridges, Diane Sawyer, Bryan White
- Episode 146 : Marilu Henner, Kristin Scott Thomas, Alan Jackson
- Episode 147 : Ron Howard, Patrick Ewing, Gene Catron
- Episode 148 : Tony Randall, Wendy Liebman, Helena Bonham Carter
- Episode 149 : Stupid Pet Tricks, Anthony Edwards, Natalie Cole
- Episode 150 : Sarah Ferguson, Derek Jeter, Reba McEntire
- Episode 151 : Heather Locklear, Sinbad, Tony Toni Tone
- Episode 152 : Glenn Close, Marc Maron, Eriq LaSalle
- Episode 153 : Phil Hartman, Bob Costas, Luther Vandross
- Episode 154 : Kid Inventors, Will Smith, Jimmy Buffett
- Episode 155 : Lisa Kudrow, Delroy Lindo, Wynonna
- Episode 156 : Jeff Daniels, Dolly Parton
- Episode 157 : Martin Short, Scott Bryan, Rita Wilson
- Episode 158 : Lea Thompson, Natalie Portman, Stone Temple Pilots
- Episode 159 : Teri Hatcher, Brent Spiner, Luscious Jackson
- Episode 160 : John Cleese, Martha Stewart, David Copperfield
- Episode 161 : Nicole Kidman, Laura Dern, Gloria Estefan
- Episode 162 : Kenneth Branaugh, Bonnie Hunt, Counting Crows
- Episode 163 : James Woods, Bob Odenkirk, Counting Crows
- Episode 164 : Albert Brooks, Beavis & Butthead, Neil Diamond
- Episode 165 : Drew Barrymore, Mathias Pakula, Faith Hill
- Episode 166 : Andie MacDowell, Jimmie Walker, Rhett Atkins
- Episode 167 : Harry Connick Jr., Walter Cronkite
- Episode 168 : Richard Simmons, Neve Campbell, Dave Matthews Band
- Episode 169 : Billy Crystal, Cuba Gooding Jr., Darlene Love
- Episode 170 : John Travolta, Julianna Marguiles, St. Luke's Bottle Band
- Episode 171 : Nathan Lane, Kelly Preston, Rich Hall
- Episode 172 : Jane Pauley, Robert Pastorelli, Blues Traveler
- Episode 173 : Mary Tyler Moore, Jerry O'Connell, Oseola McCarty, Deana Carter
- Episode 174 : Tom Arnold, Kamarr, Joe Queenan
- Episode 175 : Alec Baldwin, Cast of Chicago
- Episode 176 : Courtney Cox, Lee Marek, Damon Hill
- Episode 177 : Kids Tell Jokes, Tracey Ullman, B.B. King
- Episode 178 : Ray Liotta, Norm MacDonald
- Episode 179 : Woody Harrelson, Jackie Chan, John Pizzarelli
- Episode 180 : Matt Dillon, Rebecca Ramijn, Cassandra Wilson
- Episode 181 : Eddie Murphy, Dwight Yoakam, Veronica Paridee
- Episode 182 : Kevin Spacey, Madeline Kahn, Harry Hill
- Episode 183 : Penelope Ann Miller, Skeet Ulrich, BR5-49
- Episode 184 : Chris O'Donnell, Debbie Reynolds, Yo Yo Ma, Edgar Meyer, Mark O'Conner
- Episode 185 : Tom Selleck, Art Donovan, Babyface
- Episode 186 : Kevin Kline, Kevin Sorbo, Kevin Brennan
- Episode 187 : David Schwimmer, Carmen Electra, Sheryl Crow
- Episode 188 : Tony Danza, Desmond Howard, Helena Bonham Carter
- Episode 189 : Dan Rather, Jane Leeves, Tori Amos
- Episode 190 : Matthew Perry, Natasha Lyonne, Jewel
- Episode 191 : Rhea Perlman, Ray Ramano, Ice Cube
- Episode 192 : Stupid Human Tricks, Elle MacPherson, Charles Barkley
- Episode 193 : Isabella Rossellini, Billy Bob Thorton, Tokyo Shock Boys
- Episode 194 : Fran Drescher, Eva Herzigova, Tony Bennett
- Episode 195 : Pierce Brosnan, Lance Alstodt, Brian Regan
- Episode 196 : Brett Favre, David Spade, Silverchair
- Episode 197 : Stupid Pet Tricks, Brett Butler, Fugees
- Episode 198 : Sarah Jessica Parker, Geoffrey Rush, Barry Manilow
- Episode 199 : Richard Harris, Siskel & Ebert, Far East Circus
- Episode 200 : Peter O'Toole, Salma Hayek, Jazz Passengers
- Episode 201 : Terry Bradshaw, Carmen Electra, Eddie Brill
- Episode 202 : Steven Seagal, Brittany Starr, Beck
- Episode 203 : Joan Lunden, Chris Rock, Fiona Apple
- Episode 204 : Geena Davis, Martha Stewart, Robert Carlyle
- Episode 205 : Kevin Kline, Jamie Foxx, Sugar Ray
- Episode 206 : Danny DeVito, Patrick Rafter, Tim McGraw
- Episode 207 : Salma Hayek, Joan Cusak, Louie Anderson
- Episode 208 : Noah Wylie, Damon Wayons, Missy Misdemeanor Elliot
- Episode 209 : Andie MacDowell, Cynthia Cooper, Nanci Griffith & Darius Rucker
- Episode 210 : Jennifer Jason Leigh, Starr Jones, Bee Gees
- Episode 111 : George Clooney, Bill Cosby
- Episode 112 : Nicole Kidman, Gregory Hines, God's Property
- Episode 113 : Jennifer Lopez, Michael Lamonico, Bill Engvall
- Episode 114 : Alec Baldwin, Jonathan Lipnicki, Deana Carter
- Episode 115 : Kim Basinger, Ray Ramano, Jackson Browne
- Episode 116 : Fourth Anniversary Special
- Episode 117 : Fran Drescher, Ryan Tripp, Brooks & Dunn
- Episode 118 : Michael J. Fox, Sarah O'Hare, Patti Smith
- Episode 119 : Cameron Diaz, Adam Arkin, Veniamin
- Episode 120 : Matt Lauer, Ryan Kurlander, Sheryl Crow
- Episode 121 : Elle MacPherson, Jon Tenney, Elvis Costello & the Fairfield Four
- Episode 122 : Dan Aykroyd, Jack Hanna, Boyz II Men
- Episode 123 : Bryant Gumbel, Harland Williams, Everclear
- Episode 124 : John Lithgow, Christy Turlington, Foo Fighters
- Episode 125 : James Belushi, Christina Ricci, Oasis
- Episode 126 : Uma Thurman, Mark Wahlberg, Eddie Izzard
- Episode 127 : David Duchovny, Emily Mae Young, Todd Barry
- Episode 128 : Tom Brokaw, Stevie Starr, Green Day
- Episode 129 : Nathan Lane, Chalize Theron, Carly Simon
- Episode 130 : Mike Wallace, Kelly Montieth, LL Cool J
- Episode 131 : Robert Pastorelli, Harmony Korine, Smash Mouth
- Episode 132 : Mariah Carey, Anthony Clark
- Episode 133 : Maria Martiromo, Penn & Teller, Amy Grant
- Episode 134 : Ellen Barkin, Bobby Bonilla, Angelo Massagli
- Episode 135 : Kid Scientists, David Hyde Pierce, Andy Greene
- Episode 136 : Stupid Human Tricks, Naomi Campbell, Bobby Brown
- Episode 137 : John Travolta, Cybill Shepard, Kuznetsov Troupe
- Episode 138 : Danny Aiello, Helena Bonham Carter, Mandy & Dora Lee Patinkin
- Episode 139 : Sarah Ferguson, Kelly McGillis, Leann Rimes
- Episode 140 : Harry Connick Jr., Pamela Lee
- Episode 141 : Robert F. Kennedy Jr., Heather Matarazzo, B.B. King & Tracy Chapman
- Episode 142 : Wesley Snipes, Naomi Judd, Martina Hingis
- Episode 143 : Claire Danes, Michelle Kwan, Lorrie Morgan
- Episode 144 : Marv Albert, Daniel Scribner & Tylin Hall, John Fogerty
- Episode 145 : Bill Murray, Alison Eastwood, Matchbox 20
- Episode 146 : Don Rickles, Heather Graham, Lou Reed
- Episode 147 : Richard Simmons, Venus Williams, Wynonna
- Episode 148 : Tom Arnold, Kordell Stewart, Elvis Costello
- Episode 149 : Sigourney Weaver, David Brenner, Trischa Yearwood
- Episode 150 : Danny DeVito, Sarah Michelle Gellar
- Episode 151 : Kirstie Alley, Luke Perry, Shengyang Acrobats
- Episode 152 : John Cusak, Natalie Portman, Stomp with Bill Irwin
- Episode 153 : Kids Tell Jokes, Marisa Tomei, James Taylor
- Episode 154 : Stupid Pet Tricks, Anthony Edwards, Joost Elffers
- Episode 155 : Kevin Spacey, Art Donovan, Wallflowers
- Episode 156 : Jon Stewart, John Witherspoon, Days of the New
- Episode 157 : Courteney Cox, Peyton Manning, Shania Twain
- Episode 158 : Helen Hunt, Terrell Davis, Chumbawamba
- Episode 159 : Sir Anthony Hopkins, Eric Lindros, Enya
- Episode 160 : Nathan Lane, Hazelle Goodman, Mitch Fatel
- Episode 161 : Alex D Linz, Jerry O'Connell, Bryan Adams
- Episode 162 : Kevin Costner, Tyra Banks, Nina & Nickolai
- Episode 163 : Pam Grier, Tom Everett Scott, James Brown
- Episode 164 : Greg Kinnear, Djimon Hounsou, Ben Folds Five
- Episode 165 : Leslie Nelson, Michelle Yeoh, Hanson
- Episode 166 : Pierce Brosnan, Lou Holtz
- Episode 167 : Joan Lunden, Angelo Massaglini, G. Love with Special Sauce & Dr. John
- Episode 168 : Terry Bradshaw, Billy Zane, Darlene Love
- Episode 169 : Quentin Tarantino, Anne Heche, Kenny Wayne Shepard Band
- Episode 170 : Bridget Fonda, Matt Damon, Allan Harvey
- Episode 171 : Marilu Henner, Leila Kenzle, George Miller
- Episode 172 : Samuel L. Jackson, Howie Long, Louie C.K.
- Episode 173 : Tom Brokaw, Tobey Maquire, Fiona Apple
- Episode 174 : Norm MacDonald, Peta Wilson, Streb
- Episode 175 : Minnie Driver, Paul Simon, Cast of The Capeman
- Episode 176 : Penelope Ann Miller, Terry Pledger, Collective Soul
- Episode 177 : Robin Williams, Dave Chappelle, Stevie Nicks and Lindsey Buckingham
- Episode 178 : Bill Pullman, Jim Breuer, Stevie Nicks and Lindsey Buckingham
- Episode 179 : Peter O'Toole, Martin Scorcese
- Episode 180 : Kenneth Branagh, Spice Girls, Jim Nantz
- Episode 181 : Ben Stiller, Sandra Bernhard, Jars of Clay
- Episode 182 : Michael Isikoff, Sarah Ferguson
- Episode 183 : Robert Duvall, Kennedy, Emmylou Harris
- Episode 184 : Michael Keaton, Brian Williams, Blues Traveller
- Episode 185 : David Spade, Justin Miller, Jeff Garlin
- Episode 186 : Ethan Hawke, Merrill Markoe
- Episode 187 : Tom Arnold, Steve Forbes, Jake Johannsen
- Episode 188 : John Goodman, Mitch Hedberg, Jeff Gordon
- Episode 189 : Dan Akroyd, Naomi Campbell, Duncan Sheik
- Episode 190 : Dan Rather, Honeymoon the pig, Cast of Ragtime
- Episode 191 : Drew Barrymore, Shania Twain
- Episode 192 : Richard Simmons, John Elway
- Episode 193 : Bill Cosby, Blues Brothers
- Episode 194 : Stupid Human Tricks, Cindy Crawford, Jonny Moseley
- Episode 195 : Adam Sandler, Jack Hanna
- Episode 196 : Bruce Willis, LeAnn Rimes & Bryan White
- Episode 197 : Heather Locklear, Tom Selleck
- Episode 198 : Mike Myers, Paula Cole
- Episode 199 : Nathan Lane, Bingo Granny
- Episode 200 : Bob Dole, Marilyn Manson
- Episode 201 : Jean-Claude Van Damme, Darryl Strawberry, Joe Cocker
- Episode 202 : Beau Bridges, Terrell Davis, Squirrel Nut Zippers
- Episode 203 : Terry Bradshaw, Jesse Jackson
- Episode 204 : Ray Romano, Chris Cardone, Tom Agna
- Episode 205 : Stupid Human Tricks, Jason Patric, Eve 6
- Episode 206 : Richard Simmons, Luisa Conlon
- Episode 207 : Andie MacDowell, Willie Nelson
- Episode 208 : Tim Forneris, Stephen Dorff, Wynonna
- Episode 209 : Charles Grodin, Paul Hopkins
- Episode 210 : Jack Hanna, Gretchen Mol, Nick Cave & The Bad Seeds
- Episode 211 : Cindy Crawford, Jeff Greenfield, Hootie & The Blowfish
- Episode 212 : Ben Stiller, Jackie Chan, Vince Gill
- Episode 213 : Bill Cosby, George Hamilton
- Episode 114 : Denis Leary, George Hamilton
- Episode 115 : Vince Vaughn, Brian Benben, Brian Setzer Orchestra
- Episode 116 : Michael J. Fox, Evander Holyfield, Dixie Chicks
- Episode 117 : Jennifer Lopez, Meredith Viera, Lyle Lovett
- Episode 118 : Stupid Pet Tricks, Marv Albert, Kevin James
- Episode 119 : Howard Stern, Katie Holmes
- Episode 120 : Jon Stewart, Jean Reno, Rob Zombie
- Episode 121 : Fran Drescher, Chris Kattan, Elvis Costello & Burt Bacharach
- Episode 122 : Chris Tucker, Faith Ford, Eagle Eye Cherry
- Episode 123 : Kelsey Grammer, Nick Mason, Tony Bennett
- Episode 124 : Drew Carey, Billy Connolly, Hedwig & The Angry Inch
- Episode 125 : Steve Martin, Cokie Roberts
- Episode 126 : Kelly Preston, Peter Boyle, Semisonic
- Episode 127 : Elizabeth & Bob Dole, Joaquin Phoenix
- Episode 128 : Jeff Goldblum, John Mellencamp
- Episode 129 : Isabella Rossellini, Stephen Baldwin, George Miller
- Episode 130 : Joan Lunden, Jeff Altman, Sheryl Crow
- Episode 131 : Mark McGwire, Robert Benigni, Bruce Hornsby
- Episode 132 : State Fair Champions, Ringo Starr
- Episode 133 : Jeff Daniels, David Cross, Mitch Hedberg
- Episode 134 : Danny Glover, Cal Ripken Jr., R.E.M.
- Episode 135 : Naomi Campbell, David Wells, R.E.M.
- Episode 136 : Danny DeVito, Joe Torre, Eddie Brill
- Episode 137 : Martin Short, Eddie Izzard, Phish
- Episode 138 : Daniel Baldwin, Todd Solondz, Phil Collins
- Episode 139 : Holly Hunter, Hunter S. Thompson, Garbage
- Episode 140 : Ted Danson, Denny Brauer, Black Sabbath
- Episode 141 : Anthony Hopkins, Buzz Aldrin, Depeche Mode
- Episode 142 : Queen Latifah, Ellie Lammer, Darrell Hammond
- Episode 143 : Adam Sandler, Jayson Williams, Soul Coughing
- Episode 144 : Denzel Washington, Father Mike Berner
- Episode 145 : George Pataki, Evan Metropoulis, P.J. Harvey
- Episode 146 : George Michael, Col. Gail Halverson, Hanson
- Episode 147 : Luke Perry, Tom Wolfe, Jay-Z
- Episode 148 : Melanie Griffith, Walter Cronkite, Travis Tritt
- Episode 149 : Roma Downey, Kenneth Branagh, Goo Goo Dolls
- Episode 150 : Donald Trump, Doug Flutie, Sarah Silverman
- Episode 151 : Kid Scientists, Cameron Diaz, Mariah Carey
- Episode 152 : Will Smith, Jack Hanna
- Episode 153 : Cher, Jerry Springer
- Episode 154 : Christian Slater, Celine Dion & Bryan Adams
- Episode 155 : Drew Barrymore, Siskel & Ebert
- Episode 156 : Helen Hunt, Ray Romano
- Episode 157 : Geena Davis, Martha Stewart, Roger Daltry
- Episode 158 : Gwyneth Paltrow, Peter Berg, Bonnie Raitt
- Episode 159 : Michael Caine, Art Donavon, Jewel
- Episode 160 : Salma Hayek, Marilyn Manson, Caroline Rhea
- Episode 161 : Patrick Stewart, Jon Stewart, Faith Hill
- Episode 162 : Greg Kinnear, Jane Horrocks, Reggie McFadden
- Episode 163 : Tom Hanks, Brooklyn Philharmonic
- Episode 164 : Meg Ryan, Whitney Houston
- Episode 165 : Tom Brokaw, Famke Janssen, Emmylou Harris
- Episode 166 : Robin Williams, Natalie Merchant
- Episode 167 : Val Kilmer, Ricky Williams, Billy Bragg & Natalie Merchant
- Episode 168 : Susan Sarandon, Marc Weinberg, Vienna Choir Boys
- Episode 169 : Jeff Goldblum, Angelina Jolie, Third Eye Blind
- Episode 170 : Julia Roberts, David Kelly
- Episode 171 : Barbara Walters, Josh Hartnett, Cyndi Lauper
- Episode 172 : Charles Grodin, John Witherspoon, Jessye Norman
- Episode 173 : John Travolta, Darlene Love
- Episode 174 : Chazz Palminteri, Ann Curry, Rufus Wainwright
- Episode 175 : James Woods, David Brenner, Cast of But Boy Could He Sing
- Episode 176 : Jay Thomas, Vinny Testaverde, Patti Smith
- Episode 177 : Stupid Human Tricks, Nathan Lane, St. Luke's Bottle Band
- Episode 178 : Jon Voight, Jena Malone, Louie C.K.
- Episode 179 : Sarah Jessica Parker, David Remnick, Bryan Callan
- Episode 180 : Jennifer Jason Leigh, Liam Aiken, Greg Behrendt
- Episode 181 : Mira Sorvino, Terry Bradshaw
- Episode 182 : Lisa Kudrow, Terry Bradshaw, Jason Kuller
- Episode 183 : Jon Stewart, Marv Albert, Jim Gaffigan
- Episode 184 : Gillian Anderson, Charlie Rose, Black Crowes
- Episode 185 : Robert Duvall, Al Franken, B.B. King
- Episode 186 : Conan O'Brian, Alanis Morrisette
- Episode 187 : William Baldwin, Trisha Yearwood, Scott Ferrall
- Episode 188 : Jack Hanna, Patricia Arquette
- Episode 189 : Yasmine Bleeth, Adam Carolla, James Brown
- Episode 190 : Alicia Silverstone, D.L. Hughley, Second Hand
- Episode 191 : Sophia Loren, The Mavericks
- Episode 192 : Bill Murray, Shania Twain
- Episode 193 : Cate Blanchett, Jason Schwartzman, Brandy
- Episode 194 : Bill Cosby, Brendon Fraser, Ricky Scruggs & Vince Gill
- Episode 195 : Tom Arnold, David Brenner, Catherine Bell
- Episode 196 : Tom Brokaw, Sean Patrick Flanery, Creed
- Episode 197 : Mel Gibson, Laetitia Casta, Fresh Step
- Episode 198 : Stupid Pet Tricks, Martha Stewart, Mitch Hedberg
- Episode 199 : Michael J. Fox, Rev. John & Ellena Cobb, Willie Nelson
- Episode 200 : Jeff Daniels, Fernanda Montenegro, Monica
- Episode 201 : Kevin James, Sheryl Crow
- Episode 202 : Ricki Lake, Kid Rock
- Episode 203 : Craig Kilborn, Louise Smith, The Umbilical Brothers
- Episode 104 : Queen Latifah, John Popper
- Episode 105 : John McEnroe, Sharon Lawrence, Nanci Griffith
- Episode 106 : Kid Scientists, Edie Falco, Dixie Chicks
- Episode 107 : John Leguizamo, Meat Loaf
- Episode 108 : Jenna Elfman, Chris Kattan, Christine Aguilera
- Episode 109 : Heather Locklear, Keyshawn Johnson
- Episode 110 : Michael J. Fox, Heather French
- Episode 111 : Robin Williams, Norm MacDonald
- Episode 112 : Stupid Pet Tricks, Ashley Judd, Randy Travis
- Episode 113 : Mark Wahlberg, Adam Sandler, Roger Ebert
- Episode 114 : Kelly Preston, Stirling Moss, Sugar Ray
- Episode 115 : Kevin Pollak, Tom Waits
- Episode 116 : Nathan Lane, Emmylou Harris & Linda Rondstadt
- Episode 117 : Mia Farrow, Russell Crowe, Paula Cole Band
- Episode 118 : Kevin Spacey, Eurythmics
- Episode 119 : Kelsey Grammer, Rebecca Gayheart
- Episode 120 : Harrison Ford, David Bowie
- Episode 121 : Dan Quayle, Melissa Ethridge
- Episode 122 : Lili Tomlin, Leah Remini, Beth Hart
- Episode 123 : Jesse Ventura, Amy Brennamen, ZZ Top
- Episode 124 : Jack Hanna, Peter Fonda, Sting
- Episode 125 : Bruce Willis, Will Ferrell
- Episode 126 : Chazz Palminteri, Billy Blanks, Wilson Pickett
- Episode 127 : Farrah Fawcett
- Episode 128 : John Malkovich, Harland Williams
- Episode 129 : Austin Payne, Patricia Arquette, Moby
- Episode 130 : Charles Grodin, Jimmie Walker, Buena Vista Social Club
- Episode 131 : John Cusack, Bob Sarlatte, LeAnn Rimes
- Episode 132 : Martha Stewart, Martin Scorcese, Ricky Martin
- Episode 133 : Joe Torre, Denzel Washington
- Episode 134 : Meryl Streep, Natalie Merchant
- Episode 135 : Luke Perry, Jimmy Kimmel, Garbage
- Episode 136 : Lauren Holly, Jimmy Fallon, Rage Against the Machine
- Episode 137 : Bill Cosby, Milla Jovovich
- Episode 138 : Susan Sarandon, Juan Montoya, East Harlem Violinists
- Episode 139 : Regis Philbin, Mitch Hedberg
- Episode 140 : Woody Harrelson, Bobby Rahal
- Episode 141 : Don Rickles, Jane Clayson
- Episode 142 : Jack Hanna, Bob Hoskins, Melanie C
- Episode 143 : Natalie Portman, Travis Pastrana, Ted Alexandro
- Episode 144 : Stupid Human Tricks, Johnny Depp
- Episode 145 : Claudia Schiffer, Chris Cornell
- Episode 146 : Will Smith, Creed
- Episode 147 : Anthony Edwards, Yasmine Bleeth
- Episode 148 : Evander Holyfield, Ted Danson, Counting Crows
- Episode 149 : Gabriel Byrne, Mark Borchardt
- Episode 150 : Bryant Gumbel, John Carpenter, Tony Bennett
- Episode 151 : Kathie Lee Gifford, Charlotte Church
- Episode 152 : Julianna Margulies, Eric Ripert, Third Eye Blind
- Episode 153 : George Carlin, Jewel
- Episode 154 : Stupid Pet Tricks, William Baldwin
- Episode 155 : Barbara Walter, Dan Patrick, Mary J. Blige
- Episode 156 : Jenny McCarthy, Martha Stewart, Foo Fighters
- Episode 157 : Tim Robbins, Laetitia Casta, B.B. King & Dr. John
- Episode 158 : Patrick Stewart, Al Franken, Bob Marley
- Episode 159 : Geena Davis, Bill Murray, Fiona Apple
- Episode 160 : Courtney Love, Tori Murden, R.E.M.
- Episode 161 : Gwyneth Paltrow, Blondie
- Episode 162 : Danny DeVito, Harry Smith
- Episode 163 : Jim Carrey, Alanis Morrisette
- Episode 164 : Joe Breen, Jude Law
- Episode 165 : Tom Brokaw, Alex Kingston, Run DMC
- Episode 166 : Emily Watson, LL Cool J
- Episode 167 : Marv Albert, Heather Matarazzo, Bruce Henderson
- Episode 168 : Hallie Eisenberg, Jon Witherspoon, Darlene Love
- Episode 169 : Matt Damon, Q-Tip
- Episode 170 : Isabella Rossellini, Bev Tanner
- Episode 171 : Jay Thomas, Nick Nordberg
- Episode 172 : Dick Clark, Ralph Charles
- Episode 173 : Stupid Human Tricks, Kevin James, Brooklyn Philharmonic
- Episode 174 : Jeff Daniels, Jake Johannsen
- Episode 175 : Lauren Bacall, Kurt Warner
- Episode 176 : Bill Pullman, Dan Naturman
- Episode 177 : George Stephanopoulos, Sue Murphy
- Episode 178 : Edie Falco, Ray Lucas, Andy Kindler
- Episode 179 : Kate Winslet, Ice Cube
- Episode 180 : Woody Harrelson, Shawn Presser, Filter
- Episode 181 : Hillary Clinton, Art Donovan
- Episode 182 : Tom Arnold, Art Donovan, Lynryd Skynryd
- Episode 183 : Regis Philbin, Mark Borchardt
- Episode 184 : Charles Grodin, Julia Roberts, Regis Philbin
- Episode 185 : Regis Philbin, Jerry Seinfeld, Danny DeVito
- Episode 186 : Paul Schaffer, Bruce Willis, Martin Short
- Episode 187 : Regis Philbin, Bill Cosby, Sarah Jessica Parker
- Episode 188 : Paul Schaffer, Steve Martin, Billy Crystal
- Episode 189 : Paul Schaffer, Drew Barrymore, Ray Romano
- Episode 190 : David Brenner, Kathie Lee Gifford, Alec Baldwin
- Episode 191 : Tom Snyder, Norm MacDonald, Don Rickles
- Episode 192 : Tom Snyder, Mike Myers, Roseanne, Bonnie Hunt
- Episode 193 : Tom Arnold, Robin Williams, Jack Hannah
- Episode 194 : Regis Philbin, Robin Williams, Foo Fighters
- Episode 195 : Bill Cosby, Heidi Klum, Vince Carter, Dr. Paula Mahone, Dane Cook
- Episode 196 : Julia Roberts, Israel Perlman
- Episode 197 : Kathie Lee Gifford, Tom Arnold, Joy Behar, Linda Edar
- Episode 198 : John Goodman, Norm MacDonald
- Episode 199 : Drew Carey, Dolly Parton
- Episode 200 : David Brenner, Carson Daley, Aida Turturro, Gary Gulman, Ben Harper & The Innocent Criminals
- Episode 201 : Wesley Snipes, Dido
- Episode 202 : Jon Favreau, Stone Temple Pilots
- Episode 203 : Jack Hanna, Wyclef Jean, Survivor Castaways
- Episode 204 : Richard Hatch, Shaquille O'Neal
- Episode 205 : Charles Grodin, Donal Logue
- Episode 206 : Mary Tyler Moore, Papa Roach
- Episode 207 : Ricki Lake, Adam Ferrara
- Episode 208 : Rudy Giuliani, Laetitia Casta
- Episode 209 : D.L. Hughley, Tony Bennett & Diana Krall
- Episode 210 : Tim Robbins, Andy Kindler
- Episode 211 : Carson Daly, Dwight Yoakam
- Episode 212 : Renee Zellweger, Bonnie Raitt
- Episode 213 : Jamie Foxx, Ben Harper and the Innocent Criminals
- Episode 114 : Jesse Ventura, Spinal Tap
- Episode 115 : Greg Kinnear, Jake Johannsen
- Episode 116 : Marat Safin, Sting
- Episode 117 : Chris Rock, Emmylou Harris
- Episode 118 : Sally Field, Eddie Irvine
- Episode 119 : Al Gore, Crosby Stills & Nash
- Episode 120 : Kate Hudson, Supergrass
- Episode 121 : Sylvester Stallone, Rocco DiSpirito
- Episode 122 : Gabriel Byrne, Kevin James
- Episode 123 : Denzel Washington, Mark Knopfler
- Episode 124 : Ray Romano, Ralph Nader
- Episode 125 : Jada Pinkett Smith, LL Cool J
- Episode 126 : Geena Davis, Tom Cavanagh
- Episode 127 : Christine Baranski, Green Day
- Episode 128 : Farrah Fawcett, Loretta Lynn
- Episode 129 : Kevin Spacey, Lenny Krayzelberg
- Episode 130 : Magic Johnson, Jewel
- Episode 131 : Ben Stiller, Merle Haggard
- Episode 132 : Regis Philbin, Jim Gaffigan
- Episode 133 : Jason Alexander, Anthony Boudain, Foo Fighters
- Episode 134 : Martha Stewart, Spike Lee
- Episode 135 : Mark Wahlberg, Incubus
- Episode 136 : James Caan, Angela Perez Baraquio
- Episode 137 : Helen Hunt, Willie Nelson
- Episode 138 : Joaquin Phoenix, Allison Moorer
- Episode 139 : George W. Bush
- Episode 140 : Lawrence Fishburne, Lenny Kravitz
- Episode 141 : Will Smith, Derek Jeter
- Episode 142 : Show #1500
- Episode 143 : Alec Baldwin, Gil de Ferran
- Episode 144 : Kathie Lee Gifford, Mark Borchardt
- Episode 145 : Madonna
- Episode 146 : Don Rickles, Moby & Gwen Stefani
- Episode 147 : Adam Sandler, Outkast
- Episode 148 : Cokie Roberts, Patricia Arquette
- Episode 149 : Lucy Liu, Aaron Neville
- Episode 150 : Kid Scientists, Samuel L. Jackson
- Episode 151 : Bruce Willis, Charles Barkley
- Episode 152 : Mike Myers, Ricky Martin
- Episode 153 : Gwyneth Paltrow, Chris Elliot
- Episode 154 : Val Kilmer, Everclear
- Episode 155 : Susan Sarandon, Kasey Chambers
- Episode 156 : Brian Williams, Faith Hill
- Episode 157 : Richard Simmons, Giselle Bundchen
- Episode 158 : Stupid Human Tricks, Keri Russell
- Episode 159 : Matthew Broderick, David Gray
- Episode 160 : Bette Midler, Jack Hanna
- Episode 161 : Martha Stewart, Christina Aquilera
- Episode 162 : Jon Stewart, Everlast
- Episode 163 : Mel Gibson, Todd Barry
- Episode 164 : Charles Grodin, Bobby LaBonte
- Episode 165 : Jay Thomas, Orny Adams
- Episode 166 : Helen Hunt, Robert Klein
- Episode 167 : CBS Mailbag, At the Drive-In
- Episode 168 : Sean Connery, Barenaked Ladies
- Episode 169 : Tom Hanks, Darlene Love
- Episode 170 : George Clooney, Sade
- Episode 171 : Juliette Binoche, Jonathan Witherspoon
- Episode 172 : Uma Thurman, Brian Regan
- Episode 173 : Lily Tomlin, Anthony Clark
- Episode 174 : Jay Mohr, Snoop Dogg
- Episode 175 : Benjamin Bratt, Jimmie Walker
- Episode 176 : Matt Damon, Fuel
- Episode 177 : Sarah Jessica Parker, Jamie Bell
- Episode 178 : Tim Robbins, Julie Bowen
- Episode 179 : Dennis Quaid, Jason Seahorn
- Episode 180 : Kim Cattrall, Bob Sarlatte
- Episode 181 : Christine Baranski, Seal
- Episode 182 : Dan Rather, Vinnie Jones
- Episode 183 : Sean Penn, Lauren Kessler
- Episode 184 : Matthew McConaughey, Elle Macpherson
- Episode 185 : Neve Campbell, George Miller
- Episode 186 : Tom Selleck, Richard Ashcroft
- Episode 187 : John Goodman, 3 Doors Down
- Episode 188 : Dolly Parton, William Peterson
- Episode 189 : Patricia Heaton, Jeff Pobst
- Episode 190 : Keanu Reeves, Tony Siragusa
- Episode 191 : Jack Black, Aimee Mann
- Episode 192 : Anthony Hopkins, Erykah Badu
- Episode 193 : Jennifer Lopez, matchbox twenty
- Episode 194 : Marv Albert, Katie Holmes
- Episode 195 : Regis Philbin, Rod Stewart
- Episode 196 : David Boreanaz, Mitch Hedberg
- Episode 97 : Kelly Ripa, Jamie Oliver
- Episode 98 : Stupid Pet Tricks, Tom Cavanagh
- Episode 99 : Chris Rock, Spacehog
- Episode 100 : Stephanie Seymour, Nelly
- Episode 101 : Will Ferrell, Tom Dreesen
- Episode 102 : Bob Newhart, Maxwell
- Episode 103 : National Hollerin' Champions, Julia Stiles, Habib Koite & Bamada
- Episode 104 : Brooke Shields, John McEnroe, Joe Henry
- Episode 105 : Eric Kraff, Goran Ivanisevic
- Episode 106 : Connie Chung
- Episode 107 : Jason Biggs, Daniel Tosh, Etta James
- Episode 108 : Charles Grodin, Michael Franti & Spearhead
- Episode 109 : Sarah Jessica Parker, John Witherspoon
- Episode 110 : Helen Fielding, Al Lubel
- Episode 111 : Tom Arnold, Brandi Chastain, Ralph Stanley & The Whites
- Episode 112 : David Schwimmer, Bjork
- Episode 113 : Carson Daly, US Marine Corps
- Episode 114 : Tim Robbins, Amy Sedaris, Jimmy Eat World
- Episode 115 : Eugene Levy, Rich Hall
- Episode 116 : Dan Rather, Regis Philbin
- Episode 117 : Bryant Gumbel, Denis Leary, Tori Amos
- Episode 118 : Matthew Broderick, John Miller, Odetta & The Boys Choir of Harlem
- Episode 119 : Walter Cronkite, Will Ferrell, Jewel
- Episode 120 : Merideth Viera, Stephen Ambrose, Sheryl Crow, Emmylou Harris, and Gillian Welch
- Episode 121 : Rudolph Giuliani, Katie Harmon
- Episode 122 : Marcia Gay Harden, Doris Kearns Goodwin, Pete Yorn
- Episode 123 : Thomas Von Essen, Ben Stiller, Tenacious D
- Episode 124 : Hillary Clinton, Cast of '42nd Street'
- Episode 125 : Jason Alexander, Don Zimmer, Wyclef Jean
- Episode 126 : Elton John, Steve Zahn
- Episode 127 : Kate Beckinsale, Chris Kattan, Sarah Harmer
- Episode 128 : John Cusack, Grant Paulsen, Joe Strummer
- Episode 129 : Owen Wilson, Lisa Ling, Ryan Adams
- Episode 130 : Joshua Jackson, Tiki Barber, Emo Phillips
- Episode 131 : Farrah Fawcett, Tina Fey, Garbage
- Episode 132 : Tom Cavanagh, Steve Hartman, Leona Naess
- Episode 133 : Nathan Lane, Cokie Roberts
- Episode 134 : Bruce Willis, Cody Arens, Alicia Keys
- Episode 135 : Rose McGowen, Sarah Vowell, Jim Gaffigan
- Episode 136 : Steve Kroft, Bruce McCall, John Mellencamp
- Episode 137 : Jack Hannah, Justin Long, Daniel Rodriguez
- Episode 138 : Ethan Hawke, Judith Miller, Quincy Jones
- Episode 139 : John McCain, Brittany Murphy, Macy Gray
- Episode 140 : Kevin Kline, Richard Holbrooke, Caroline Rhea
- Episode 141 : David Hyde Pierce, U2
- Episode 142 : David Spade, Marv Albert, Laurie Anderson
- Episode 143 : Kevin Spacey, Amy Sedaris
- Episode 144 : Tom Brokaw, Gene Catron
- Episode 145 : John Travolta, Harland Williams
- Episode 146 : Jack Black, Tony Bennett
- Episode 147 : Billy Crystal, Brittany Spears
- Episode 148 : Marge Helgenberger, Gil de Ferran, Lyle Lovett
- Episode 149 : Stupid Pet Tricks, Vince Vaughn, Faith Evans
- Episode 150 : Richard Dreyfus, Brett Butler
- Episode 151 : Martin Lawrence, Natalie Merchant
- Episode 152 : Barbara Walters, David Radcliffe, Natalie Merchant
- Episode 153 : Harry Connick Jr., Bernie Mac
- Episode 154 : Steve Martin, Earl Scruggs
- Episode 155 : Richard Harris, George Carlin
- Episode 156 : Kevin James, Deion Sanders
- Episode 157 : Julia Roberts, Shelby Lynne
- Episode 158 : Jenna Elfman, Kid Rock
- Episode 159 : David Sedaris, Five for Fighting
- Episode 160 : Ray Romano, Mitch Hedberg
- Episode 161 : Kelly Ripa, Mort Sahl
- Episode 162 : George Clooney, Martha Stewart
- Episode 163 : Noah Wyle, George Miller, Carole King
- Episode 164 : Julia Stiles, Jeff Gordon
- Episode 165 : Jada Pinkett Smith, Thomas Friedman
- Episode 166 : Ellen DeGeneres, Dave Gorman, Kelly Goldsmith
- Episode 167 : Mariah Carey, Elijah Wood, Stereophonics
- Episode 168 : Andy Garcia, Chris Matthews
- Episode 169 : Kid Scientists, Liv Tyler, Cake
- Episode 170 : Michelle Pfeiffer, Dennis Regan
- Episode 171 : Meg Ryan, Diana Krall
- Episode 172 : Kevin Spacey, Jerome Bettis, Jane Monheit
- Episode 173 : Jamie Foxx, Rhys Ifans, Darlene Love
- Episode 174 : Marisa Tomei, Lenny Kravitz
- Episode 175 : Peter Jennings, Tom Ryan
- Episode 176 : Ian McKellan, Phil Simms
- Episode 177 : Rudolph Giuliani, P.O.D.
- Episode 178 : Lauren Graham, Eddie Brill
- Episode 179 : Gwyneth Paltrow, Starsailor
- Episode 180 : Cate Blanchett, Timothy Treadwell
- Episode 181 : Jennifer Connelly, Colin Soloway
- Episode 182 : Jack Black, Foo Fighters
- Episode 183 : Tom Cruise, Tom Papa
- Episode 184 : Ethan Zohn, Josh Hartnett, Remy Zero
- Episode 185 : Cuba Gooding Jr., Jewel
- Episode 186 : David Brenner, Howie Long, Jewel
- Episode 187 : Cynthia Nixon, Mario Andretti, Willie Nelson & Rob Thomas
- Episode 188 : Darrell Hammond, Elayne Boosler, Willie Nelson & Lyle Lovett
- Episode 189 : Jimmy Kimmell, Julie Bowen, Cracker
- Episode 190 : Bruce Willis, Ivan Neville
- Episode 191 : Tim Russert, Jason Schwartzman
- Episode 192 : Merv Griffin, Phantom Planet
- Episode 193 : Regis Philbin, Steven Wright
- Episode 194 : LL Cool J, John McEnroe
- Episode 195 : Amy Brenneman, Martin Rees, Shakira
- Episode 196 : Adam Vinatieri, Chris Matthews
- Episode 197 : Mariska Harkitay, George Divoky, Alan Jackson
- Episode 98 : Andy Richter, Jake Johannsen
- Episode 99 : Janet Jackson, Enrique Iglesias
- Episode 100 : Denis Leary, India.Arie
- Episode 101 : Amanda Peet, Tom Dreesen
- Episode 102 : Jeff Goldblum, George Miller
- Episode 103 : Drea de Matteo, Sarah Vowell, The Doves
- Episode 104 : Peter Jennings, John Witherspoon
- Episode 105 : John McEnroe, Piper Perabo, Queens of the Stone Age
- Episode 106 : Jennifer Esposito, Marianne Faithful
- Episode 107 : Bill Clinton, Nanci Griffith
- Episode 108 : Regis Philbin, Linda Thompson
- Episode 109 : Megan Mullally, Rich Hall
- Episode 110 : Bruce Willis, Eve
- Episode 111 : Jack Hanna, Tom Cavanagh, Civil War Reenactment
- Episode 112 : Reese Witherspoon, Juan Montoya, India.Arie
- Episode 113 : Rose McGowan, Phillipe Petit
- Episode 114 : Lauren Graham, Colin Quinn
- Episode 115 : Patricia Heaton, Murray Walker
- Episode 116 : David Schwimmer, Avril Lavigne
- Episode 117 : Anthony LaPaglia, Effie Nielson, Clinic
- Episode 118 : Edward Norton, John Mayer
- Episode 119 : David Arquette, Todd Lynn
- Episode 120 : Jennifer Love Hewitt, Tom Petty and The Heartbreakers
- Episode 121 : John McCain, David Sedaris
- Episode 122 : Charles Barkley, Franco Zeffirelli, Nitty Gritty Dirt Band
- Episode 123 : Michelle Pfeiffer, Bon Jovi
- Episode 124 : Johnny Knoxville, Ron White
- Episode 125 : Debra Messing, Pink
- Episode 126 : Thandie Newton, Faith Hill
- Episode 127 : Rudolph Giuliani, Naomi Watts
- Episode 128 : Samuel L. Jackson, Santana & Michelle Branch
- Episode 129 : P. Diddy, Eddie Brill
- Episode 130 : Bonnie Hunt, Christina Aquilera
- Episode 131 : Salma Hayek, Tori Amos
- Episode 132 : Warren Zevon
- Episode 133 : Jerry Seinfeld, Foo Fighters
- Episode 134 : Don Rickles, Jim Gaffigan
- Episode 135 : Stupid Human Tricks, Sean Hayes, Willie Nelson & Ryan Adams
- Episode 136 : Julianne Moore, Grant Paulsen, Blind Boys of Alabama
- Episode 137 : Kid Inventors, Tom Brokaw, The Wallflowers
- Episode 138 : Brittany Murphy, Al Lubel
- Episode 139 : Robin Williams, Emily Proctor
- Episode 140 : Kelly Ripa, Emmitt Smith, Missy Elliott
- Episode 141 : Barbara Walters, Joe Pantoliano
- Episode 142 : Maggie Gyllenhaal, Pearl Jam
- Episode 143 : Al Gore, Pearl Jam
- Episode 144 : Kevin James, matchbox 20
- Episode 145 : Shania Twain, Cristiano da Matta
- Episode 146 : Adam Sandler, Pussycat Dolls
- Episode 147 : Ice Cube, Cast of Hairspray
- Episode 148 : Harry Connick Jr., Larry Miller
- Episode 149 : Stupid Pet Tricks, Lisa Kudrow, Audioslave
- Episode 150 : George Clooney, Jack Hanna
- Episode 151 : Ray Romano, Jurassic 5
- Episode 152 : Amy Sedaris, The Strokes
- Episode 153 : Liza Minnelli, Jann Karam
- Episode 154 : Jennifer Lopez, Sum 41
- Episode 155 : Jason Alexander, Ryan Adams
- Episode 156 : Nia Vardalos, Barry Sonnenfeld
- Episode 157 : Allison Janney, Martin Scorsese
- Episode 158 : Natasha Richardson, Mike Birbiglia, David Gray
- Episode 159 : Catherine Zeta-Jones, Coldplay
- Episode 160 : Drew Barrymore, Rod Stewart
- Episode 161 : Denzel Washington, Daniel Bouloud
- Episode 162 : Tom Hanks, Phish
- Episode 163 : Liv Tyler, Jay Thomas, Darlene Love
- Episode 164 : Ashton Kutcher, Jason Kidd
- Episode 165 : Isabella Rossellini, Mort Sahl
- Episode 166 : Michael Caine, George Foreman
- Episode 167 : Richard Gere, Chris Elliott
- Episode 168 : Merv Griffin, Interpol
- Episode 169 : Renee Zellweger, Chuck Barris
- Episode 170 : Andy Richter, Rich Hall
- Episode 171 : Jimmy Kimmel, Simon Baker
- Episode 172 : Claire Danes, Bob Sarlatte
- Episode 173 : Sandra Bullock, Marv Albert
- Episode 174 : George Clooney, Soundtrack of Our Lives
- Episode 175 : Joan Rivers, Kathleen Edwards
- Episode 176 : Simon Cowell, Topher Grace, Vienna Teng
- Episode 177 : Regis Philbin, John C. Reilly
- Episode 178 : Tina Fey, Jonathan Ames, Johnny Marr & The Healers
- Episode 179 : Ellen DeGeneres, Zwan
- Episode 180 : Bonnie Hunt, John Witherspoon
- Episode 181 : Show #1944Kate Hudson, Jack Hanna
- Episode 182 : Matthew McConaughey, John Gruden, The Roots
- Episode 183 : Kelsey Grammer, Michael Tong, B.B. King and Shemeika Copeland
- Episode 184 : Stupid Pet Tricks, Tom Brokaw, The Pretenders
- Episode 185 : Brendan Fraser, Kids in The Hall, Bonnie Raitt, Keb' Mo, Kim Wilson
- Episode 186 : Matthew Broderick, Tony Bennett & k.d. Lang
- Episode 187 : Amy Brennamen, Nate Erwin, Vince Gill
- Episode 188 : Queen Latifah, Colin Quinn, Lou Reed
- Episode 189 : Kid Scientists, Kurt Russell
- Episode 190 : Kate Winslet, Dennis Regan, Rufus Wainwright
- Episode 191 : Dr. Phil, Beck
- Episode 192 : Vince Vaughn, Sarah Vowel, Beck
- Episode 193 : Kevin Spacey, Reggie Miller
- Episode 194 : Champion Turkey Callers, Marg Helgenberger, The Flaming Lips
- Episode 195 : Jeff Daniels, Lynne Cox, Steven Wright
- Episode 196 : Steve Martin, Foo Fighters
- Episode 197 : Stupid Human Tricks, Sharon Osborne, Norah Jones
- Episode 198 : Bruce Willis, Dan Rather, Carmen Electra, Brian Kiley
- Episode 199 : John McEnroe, Tom Arnold, Eric Ripert, Todd Barry, Jason Mras
- Episode 200 : Regis Philbin, Charles Grodin, Susan Lucci, Greg Giraldo, Kathleen Edwards
- Episode 201 : Al Franken, Grant Paulsen
- Episode 202 : Craig Kilborn, Dave Salmoni, Kings of Leon
- Episode 203 : Gen. Tommy Franks, Rodney Crowell
- Episode 204 : Nicolas Cage, Alton Brown
- Episode 205 : Whoopi Goldberg, Vic Henley, Ima Robot
- Episode 206 : Andy Roddick, Jack Black, Warren Zevon*
- Episode 207 : Salma Hayek, Chris Elliott
- Episode 208 : Sharon Stone, The Raveonettes
- Episode 109 : Regis Philbin, Seal
- Episode 110 : Cuba Gooding Jr., Simon & Garfunkel
- Episode 111 : Dr. Phil, David Bowie
- Episode 112 : Ben Stiller, Elvis Costello
- Episode 113 : The Rock, Lynne Cheney
- Episode 114 : Colin Powell, Jennifer Garner
- Episode 115 : Joe Pantaliano, Kevin Nealon, Outkast
- Episode 116 : Denzel Washington, New York Philharmonic
- Episode 117 : Tom Cavanagh, Ray Wald, Dido
- Episode 118 : Tim Robbins, Sting
- Episode 119 : Stupid Human Tricks, Lisa Kudrow, R.E.M.
- Episode 120 : Robin Williams, Summerwind Skippers
- Episode 121 : Jessica Simpson, Rufus Wainwright
- Episode 122 : Uma Thurman, Ricky Gervais, Renee Fleming
- Episode 123 : Amy Sedaris, Tom Dreesen, Anthony Hamilton
- Episode 124 : George Clooney, Merle Haggard
- Episode 125 : Charlie Sheen, John Mayer
- Episode 126 : Halle Berry, Lance Armstrong
- Episode 127 : John Cusack, Scott Dixon, Hot Hot Heat
- Episode 128 : Katie Holmes, Brian Greene, Jonny Lang
- Episode 129 : Dustin Hoffman, Jamie Oliver
- Episode 130 : Darrell Hammond, Radiohead
- Episode 131 : Kiefer Sutherland, Emmylou Harris
- Episode 132 : Courteney Cox, Doris Roberts
- Episode 133 : Keanu Reeves, Sue Johanson
- Episode 134 : Eric McCormack, Dante Hall
- Episode 135 : Pamela Anderson, Amanda Lollar, Bubba Sparxx
- Episode 136 : Ashley Judd, Richard Belzer, Sarah McLachlan
- Episode 137 : Regis Philbin, Amy Brenneman
- Episode 138 : Will Ferrell, Jack McKeon, Lyle Lovett
- Episode 139 : Howard Stern, Iggy Pop with Sum 41
- Episode 140 : Lauren Graham, Paul Tracey, Wyclef Jean
- Episode 141 : Norm MacDonald, Jack Hannah
- Episode 142 : Madonna, Chris Elliot
- Episode 143 : Tom Brokaw, Dolly Parton
- Episode 144 : Russell Crowe, Pink
- Episode 145 : Jessica Lynch, Shelby Lynne
- Episode 146 : Stupid Pet Tricks, Cate Blanchett
- Episode 147 : Dakota Fanning, Rocco DiSpirito, Cast of Wicked
- Episode 148 : Alec Baldwin, Freddy Adu, Cyndi Lauper
- Episode 149 : Wesley Clark
- Episode 150 : Robert Downey Jr., Joss Stone
- Episode 151 : Paul Newman, Clay Aiken
- Episode 152 : Tom Ridge, Puddle of Mudd
- Episode 153 : Mike Myers, Jay-Z
- Episode 154 : Tom Arnold, Moby
- Episode 155 : Jessica Alba, Wendy Liebman, The Rapture
- Episode 156 : Matt Damon, Jack Johnson and G. Love
- Episode 157 : Danny DeVito, Tim Russert
- Episode 158 : Amanda Peet, Barry Sonnenfeld
- Episode 159 : Kirsten Dunst, Rod Stewart
- Episode 160 : Julia Roberts, Alkaline Trio
- Episode 161 : Liv Tyler, John Witherspoon, Alicia Keys
- Episode 162 : Barbara Walters, Sandra Diaz-Twine
- Episode 163 : Neve Campbell, Wellwater Conspiracy
- Episode 164 : Bonnie Hunt, Dave Matthews
- Episode 165 : Charlize Theron, Dave Matthews
- Episode 166 : Steve Martin, Shannon Eis
- Episode 167 : Renee Zellweger, Darlene Love
- Episode 168 : Jennifer Aniston, Ryan Adams
- Episode 169 : Jennifer Connelly, Christopher Paolini
- Episode 170 : Eddie Griffin, Marv Albert
- Episode 171 : Nathan Lane, Ruben Studdard
- Episode 172 : Billy Bob Thornton
- Episode 173 : Patricia Heaton, Kate Bosworth
- Episode 174 : Jeff Daniels, Isaiah Thomas, The Shins
- Episode 175 : Bette Midler, Howie Day
- Episode 176 : Dave Chapelle, Carmen Electra
- Episode 177 : Christina Aquilera, Gary Muledeer
- Episode 178 : Jessica Simpson & Nick Lachey, Al Green
- Episode 179 : Ashton Kutcher, Paula Abdul
- Episode 180 : Kristin Davis, Joe Simpson
- Episode 181 : Matthew Broderick, Jim Garvin
- Episode 182 : Al Franken, Jake Johannsen, Phantom Planet
- Episode 183 : Regis Philbin, The Thrills
- Episode 184 : Harry Connick Jr., Sean Astin
- Episode 185 : Bill Belichick, Cindy Crawford
- Episode 186 : Hilary Swank, Todd Barry, Nellie McKay
- Episode 187 : Dr. Phil, Tara Dakides, Clip of The Beatles
- Episode 88 : Drew Barrymore, Jack Hanna
- Episode 89 : Adam Sandler, Eve
- Episode 90 : Bill Murray, Jermaine O'Neal
- Episode 91 : Alec Baldwin, Sofia Coppola, Kylie Minogue
- Episode 92 : Stupid Human Tricks, Ray Romano, Kayne West
- Episode 93 : Kelly Ripa, Lindsay Lohan
- Episode 94 : Ashley Judd, Ben Harper
- Episode 95 : Gordon Geisbrecht, Sarah Jessica Parker, Nelly Furtado
- Episode 96 : Amber Tamblyn, Brian Regan, Leona Naess
- Episode 97 : Jeff Goldblum, Norah Jones
- Episode 98 : Edie Falco, Steven Bailey, Edie Brickell
- Episode 99 : Diane Sawyer, Benjamin McKenzie
- Episode 100 : Stupid Pet Tricks, Tim Robbins, Evanescence
- Episode 101 : Jon Cryer, Chris Kentis, Renee Olstead
- Episode 102 : Dennis Leary, Sam Easterson
- Episode 103 : Paul Hamm, Josh Hartnett, Nick Cave
- Episode 104 : Natalie Coughlin, Carla Gugino, Gavin DeGraw
- Episode 105 : Maureen Dowd, Tom Ryan
- Episode 106 : Carly Patterson, Jeff Foxworthy, LL Cool J
- Episode 107 : Farrah Fawcett, The Clarks
- Episode 108 : John McCain, Tom Russell
- Episode 109 : Tim Russert, Snow Patrol
- Episode 110 : Jane Pauley, Greg Giraldo
- Episode 111 : National Hollerin' Champions, Neve Campbell, Keane
- Episode 112 : Regis Philbin, Hoobastank
- Episode 113 : Martin Short, Alan Jackson
- Episode 114 : Ray Romano, Avril Lavigne
- Episode 115 : Drew Barrymore, Aron Ralston
- Episode 116 : John Kerry, Green Day
- Episode 117 : Dr. Phil, Gary Sinise
- Episode 118 : Kelly Ripa, Annie Duke, Elvis Costello
- Episode 119 : Stupid Human Tricks, Rob Lowe, Mos Def
- Episode 120 : Julianne Moore, Tom Dreesen
- Episode 121 : Queen Latifah, Jack Hanna
- Episode 122 : John Goodman, Tom Waits
- Episode 123 : Joaquin Phoenix, Austin Stevens, Switchfoot
- Episode 124 : John Travolta, Tim Frisby, Pearl Jam
- Episode 125 : Richard Gere, Jason Randal
- Episode 126 : Howard Dean, Franz Ferdinand
- Episode 127 : Annette Bening, Bill O'Reilly
- Episode 128 : Jamie Foxx, Davy Rothbart
- Episode 129 : Donald Trump, Brian Binnie, Minnie Driver
- Episode 130 : Brooke Shields, Barry Sonnenfeld
- Episode 131 : Melina Kanakaredes, Paul Teutul Sr. and Paul Teutul Jr., Ben Harper and the Blind Boys of Alabama
- Episode 132 : Laura Linney, Richard Lewis, The Wallflowers and Jordan Zevon
- Episode 133 : Jennifer Lopez, Sue Johanson
- Episode 134 : Billy Crystal, Ralph Nader
- Episode 135 : Tony Danza, Emma Roberts, Brian Regan
- Episode 136 : Jimmy Carter, Brandi Chastain, John Mellencamp
- Episode 137 : Jude Law, Ricky Gervais
- Episode 138 : Sarah Michelle Gellar, Tony Kanaan, Sparta
- Episode 139 : Dustin Hoffman, Joss Stone
- Episode 140 : Amy Sedaris, Tommy Lee
- Episode 141 : Johnny Damon, Anne Heche, The Donnas
- Episode 142 : Tom Brokaw, Mischa Barton
- Episode 143 : Rosie Perez, Steven Wright
- Episode 144 : Al Franken, Kristin Bell
- Episode 145 : Tom Hanks, Nelly
- Episode 146 : Salma Hayek, Sebastian Bourdais, Jimmy Eat World
- Episode 147 : Pierce Brosnan, Nigella Lawson, Renee Fleming
- Episode 148 : Matthew Broderick, Rosario Dawson, Los Lonely Boys
- Episode 149 : Paul Reubens, Evangeline Lilly, Project Bandaloop
- Episode 150 : Jerry Seinfeld, Jamie Oliver
- Episode 151 : Nicolas Cage, Jason Alexander, Morrissey
- Episode 152 : Renee Zellweger, Chris Raxworthy
- Episode 153 : Howard Stern, Alanis Morissette
- Episode 154 : Tom Brady, Damien Fahey
- Episode 155 : Stupid Pet Tricks, Colin Farrell, The Walkmen
- Episode 156 : Kevin Spacey, Ben Roethlisberger, Streb
- Episode 157 : Whoopi Goldberg, Jason Bateman, Marilyn Manson
- Episode 158 : Natalie Portman, John Mayer
- Episode 159 : Barack Obama, Jessica Biel
- Episode 160 : Matt Damon, Lance Armstrong
- Episode 161 : Alec Baldwin, Ken Jennings
- Episode 162 : Stupid Human Tricks, Noah Wylie, Sum 41
- Episode 163 : Sharon Reed, Tyra Banks, Lyle Lovett
- Episode 164 : Bonnie Hunt, Alex Zanardi
- Episode 165 : Jim Carrey, Ashanti
- Episode 166 : Cate Blanchett, Craig Ferguson, The Pixies
- Episode 167 : Adam Sandler, Sharon Ice
- Episode 168 : Kate Beckinsale, Ciara and Missy Elliot
- Episode 169 : Jeff Goldblum, Terrell Owens
- Episode 170 : Bill Murray, Kaki King
- Episode 171 : Dennis Quaid, Rusty Wallace, Kaki King
- Episode 172 : Kristin Johnson, Tom Dreesen
- Episode 173 : Regis Philbin, Jay Thomas, Darlene Love
- Episode 174 : Hilary Swank, Andy Dick, Green Day
- Episode 175 : Ethan Hawke, Maria Menounos, Alicia Keys
- Episode 176 : Kiefer Sutherland, Marv Albert, The Black Keys
- Episode 177 : Michael Keaton, Jamie Lynn Spears
- Episode 178 : Kevin Bacon, Caroline Rhea, Wilco
- Episode 179 : Samuel L. Jackson, Amy Poehler, B.B. King
- Episode 180 : Randy Johnson, Aisha Tyler, Razorlight
- Episode 181 : Rudolph Giuliani, Daniel Banks
- Episode 182 : Marge Helgenberger, Ryan Seacrest, My Chemical Romance
- Episode 183 : Amy Sedaris, Andy Kindler
- Episode 184 : Jack Hanna, Teri Polo
- Episode 185 : Ice Cube, Chris Russo, Interpol
- Episode 186 : Harvey Fierstein, Regina King, Steven Van Zandt, ... And You Will Know Us By the Trail of Dead
- Episode 187 : Robert Downey Jr., Nicole Richie
- Episode 188 : Jerry Lewis, Sophia Bush
- Episode 189 : Peter Lassally, Doc Severinson
- Episode 90 : Debra Messing, Peyton Manning
- Episode 91 : Patricia Heaton, John Witherspoon, Gibson/Baldwin Grammy Jazz Ensembles
- Episode 92 : Elton John, Eva Mendes
- Episode 93 : Al Franken, Matthew Fox, Nanci Griffith
- Episode 94 : Will Smith, Tom Brady
- Episode 95 : Kevin James, Aishwarya Rai, Three Doors Down
- Episode 96 : David Hyde Pierce, Howie Day
- Episode 97 : Billy Crystal, Patrick Lawler
- Episode 98 : Paris Hilton, Bill Burr
- Episode 99 : Dr. Phil, Unwritten Law
- Episode 100 : Kid Scientists, Keanu Reeves, Michael Buble
- Episode 101 : Show #2414
- Episode 102 : Show #2415
- Episode 103 : Show #2416
- Episode 104 : Show #2417
- Episode 105 : Show #2418
- Episode 106 : Show #2419
- Episode 107 : Show #2420
- Episode 108 : Show #2421
- Episode 109 : Show #2422
- Episode 110 : Show #2423
- Episode 111 : Show #2424
- Episode 112 : Show #2425
- Episode 113 : Show #2426
- Episode 114 : Show #2427
- Episode 115 : Show #2428
- Episode 116 : Show #2429
- Episode 117 : Show #2430
- Episode 118 : Show #2431
- Episode 119 : Show #2432
- Episode 120 : Show #2433
- Episode 121 : Show #2434
- Episode 122 : Show #2435
- Episode 123 : Show #2436
- Episode 124 : Show #2437
- Episode 125 : Show #2438
- Episode 126 : Show #2439
- Episode 127 : Show #2440
- Episode 128 : Show #2441
- Episode 129 : Show #2442
- Episode 130 : Show #2443
- Episode 131 : Show #2444
- Episode 132 : Show #2445
- Episode 133 : Show #2446
- Episode 134 : Show #2447
- Episode 135 : Show #2448
- Episode 136 : Show #2449
- Episode 137 : Show #2450
- Episode 138 : Show #2451
- Episode 139 : Show #2452
- Episode 140 : Show #2453
- Episode 141 : Jennifer Aniston, 50 Cent
- Episode 142 : Matthew Broderick, Teri Garr
- Episode 143 : Kelly Ripa, Hilary Duff
- Episode 144 : Steve Martin, the Teutul family from American Chopper
- Episode 145 : Ted Koppel, Jim Gaffigan, Trey Anastasio
- Episode 146 : Kid scientists, John Cusack
- Episode 147 : Joaquin Phoenix, Trisha Yearwood
- Episode 148 : Ellen DeGeneres, Brad Paisley
- Episode 149 : Howard Stern, Pharrell Williams
- Episode 150 : Sen. John McCain, Carla Gugino
- Episode 151 : George Clooney, Ashlee Simpson
- Episode 152 : Dennis Quaid, Donovan McNabb
- Episode 153 : Stupid Pet Tricks, Claire Danes, Big Boi
- Episode 154 : Megan Mullally, John Mayer Trio
- Episode 155 : John Malkovich, NASCAR Nextel Cup winner, Jim Gaffigan
- Episode 156 : Stupid Human Tricks, Amanda Peet
- Episode 157 : Regis Philbin, Colin Hanks
- Episode 158 : Charlize Theron, Maureen Dowd
- Episode 159 : Oprah Winfrey, Bonnie Raitt
- Episode 160 : Rodeo champion Billy Etbauer
- Episode 161 : Jack Black, Reggie Bush, Sinead O'Connor
- Episode 162 : Sarah Jessica Parker, John Witherspoon
- Episode 163 : Stephen Colbert, Aqualung
- Episode 164 : Alec Baldwin, Shakira
- Episode 165 : Dr. Phil McGraw, Bill Scheft
- Episode 166 : Jim Carrey, We Are Scientists
- Episode 167 : Bonnie Hunt, Stephen A. Smith
- Episode 168 : Nathan Lane, Tom Dreesen
- Episode 169 : Jamie Foxx, Andy Kindler
- Episode 170 : Rosie Perez, Jay Thomas, Darlene Love
- Episode 171 : Heather Graham, Fall Out Boy
- Episode 172 : Bill O'Reilly, Eric Bana
- Episode 173 : Pierce Brosnan, Marv Albert
- Episode 174 : Felicity Huffman, David Rakoff, Common
- Episode 175 : Amy Sedaris, Dennis Regan, the Temptations
- Episode 176 : Albert Brooks, Kristin Cavallari
- Episode 177 : Scarlett Johannsen, Tiki Barber, Imogen Heap
- Episode 178 : Queen Latifah, Bob Sarlatte
- Episode 179 : Kiefer Sutherland, Alicia Keys, Andy Samberg
- Episode 180 : Tom Cavanagh, Jake Johannsen
- Episode 181 : Martin Lawrence, Kari Byron, Matisyahu
- Episode 182 : Tatum O'Neal, Jeff MacGregor
- Episode 183 : Kate Beckinsale, Bob Saget
- Episode 184 : Cheryl Hines, Anna Nalick, Mike Vanderjagt
- Episode 185 : Charles Grodin, Jordana Brewster
- Episode 186 : Anthony Hopkins
- Episode 187 : Bernie Mac, Beth Orton
- Episode 188 : Mischa Barton, Jeff Altman, Wicked Wisdom
- Episode 189 : Tommy Lee Jones, Anthony Hamilton
- Episode 190 : P Diddy, Train
- Episode 191 : Harrison Ford, Michael Bublé
- Episode 192 : Beyonce Knowles, Stephen A. Smith
- Episode 193 : Rachel Weisz, Beastie Boys
- Episode 194 : Senator John McCain, Heidi Klum
- Episode 95 : Martha Stewart, Michael Bublé
- Episode 96 : Geena Davis, INXS
- Episode 97 : Julianne Moore, Randy Jackson, The O'Jays
- Episode 98 : Charles Barkley, Catherine Keener
- Episode 99 : Jimmy Fallon, Hannah Teter, She Wants Revenge
- Episode 100 : Donald Trump, Bill Burr
- Episode 101 : Andy Kindler, motocross demo with Travis Pastrana, Baby Gramps
- Episode 102 : Zach Braff, Jeff Brendenburg, The Roots
- Episode 103 : Snoop Dogg, Charlie Hill, OK Go
- Episode 104 : Julianne Moore, radio-show hosts Opie and Anthony
- Episode 105 : Al Franken, Todd Snider
- Episode 106 : Maria Sharapova, Martha Stewart, Justin Timberlake
- Episode 107 : Ashton Kutcher, Sam Hornish, Jr., TV on the Radio
- Episode 108 : Dwayne The Rock Johnson, Norm MacDonald
- Episode 109 : Anne Heche, Luke Ravenstahl, The Who
- Episode 110 : Johnny Knoxville, Rachael Ray
- Episode 111 : Dr. Phil McGraw, Willie Tyler and Lester, Sekou Bunch
- Episode 112 : Patrick Dempsey, Jay Johnson and Darwin, Kasabian
- Episode 113 : Marg Helgenberger, Ronn Lucas and Scorch, Diana Krall
- Episode 114 : Ted Turner, Jeff Dunham and Walter, Fergie
- Episode 115 : LeBron James, Todd Oliver and Irving, Ludacris
- Episode 116 : Ray Liotta, Elvis Costello & Tony Bennett, Billy Garcia
- Episode 117 : Billy Bob Thornton, Lily Capehart, Sean Lennon
- Episode 118 : Amanda Peet, Nigella Lawson, Bob Seger
- Episode 119 : Sir Richard Branson, Dane Cook, Monica
- Episode 120 : Nathan Lane, Jeff Caldwell
- Episode 121 : Pete Rose, Roy Wood Jr., Cecilia Mansilla
- Episode 122 : Andy Dick, Keith Olbermann, Brazilian Girls
- Episode 123 : Alec Baldwin, Vladae the Dog Wizard, Jerry Lee Lewis & Neil Young
- Episode 124 : Frank Caliendo, Rachael Harris, Xzibit, Phil Pfister
- Episode 125 : Amy Sedaris, Trey Anastasio
- Episode 126 : Robin Williams, J.P. Calderon, Sam Moore with Wynonna
- Episode 127 : Nicky Hilton, Bob Woodward, Joseph Arthur
- Episode 128 : Jon Stewart, Nick Lachey
- Episode 129 : Katie Couric, Brian Kiley, Alan Jackson
- Episode 130 : Diddy, Neil Patrick Harris
- Episode 131 : Tom Arnold, Brian Regan, the latest Survivor: Cook Islands castaway
- Episode 132 : Tina Fey, Mike Golic & Mike Greenberg, The Killers
- Episode 133 : Julia Louis-Dreyfus, Jay Thomas, John Legend
- Episode 134 : Tim Robbins, Gene Rurka, Russell Thompkins Jr. and The New Stylistics
- Episode 135 : Bill O'Reilly, Jeff Altman, Tilly and the Wall
- Episode 136 : Borat, Tiki Barber, Beck
- Episode 137 : Rachel Weisz, David Rakoff, Morningwood
- Episode 138 : Gary Sinise, Joanne Carson, Jim Norton
- Episode 139 : Rosie O'Donnell, Lady Sovereign
- Episode 140 : Martin Short, Kinky Friedman
- Episode 141 : Will Ferrell, Jack Hanna
- Episode 142 : Dustin Hoffman, Jamie Oliver, The Metropolitan Opera
- Episode 143 : Kiefer Sutherland, Jenna Fischer, Rocco DeLuca
- Episode 144 : Daniel Craig, documentary film subject Teri Horton, Elvis Costello, Rosanne Cash
- Episode 145 : Robin Williams, Rich Little, George Jones
- Episode 146 : Jack Black & Kyle Gass, Fred Travalena, Tenacious D
- Episode 147 : Ellen DeGeneres, Gordie Brown, +44
- Episode 148 : Christopher Guest, Frank Caliendo, The Game
- Episode 149 : Sen. John Edwards, Kevin Pollak, Will Arnett
- Episode 150 : Jerry Seinfeld, Dan Patrick
- Episode 151 : Hugh Jackman, Chris Elliott, Jimmie Johnson
- Episode 152 : Matthew Broderick, Lupe Fiasco & Jill Scott
- Episode 153 : Eugene Levy, John Mayer
- Episode 154 : Helen Hunt, DJ Shadow, Q-Tip and Lateef
- Episode 155 : Kate Winslet, Tom Waits
- Episode 156 : George Clooney, The Decemberists
- Episode 157 : Richard Simmons, Kate Walsh, Ciara
- Episode 158 : Jennifer Connelly, Tom Dreesen, Shiny Toy Guns
- Episode 159 : Danny DeVito, 16-year-old duct tape expert William Beacom, Silversun Pickups
- Episode 160 : Matt Damon, Barbara Walters
- Episode 161 : Howard Stern, Gwen Stefani
- Episode 162 : Kid Scientists, Regis Philbin, Robert Randolph
- Episode 163 : Will Smith, Evanescence
- Episode 164 : Clint Eastwood, Matthew Fox
- Episode 165 : Frank Caliendo as John Madden, Ben Stiller, Rodrigo & Gabriela
- Episode 166 : Beyonce, Marv Albert, The Dears
- Episode 167 : Renée Zellweger, holiday toy demonstration, Taking Back Sunday
- Episode 168 : Tom Brokaw, Cold War Kids
- Episode 169 : Cate Blanchett, Jay Thomas, Darlene Love
- Episode 170 : Martin Short, Donal Logue
- Episode 171 : Matt Lauer, Artie Lange, Augustana
- Episode 172 : Cedric the Entertainer, Wesley Autrey, Switchfoot
- Episode 173 : Donald Trump, Mary Lynn Rajskub
- Episode 174 : David Arquette, Jennifer Hudson
- Episode 175 : Penelope Cruz, Gary Mule Deer, Ben E. King
- Episode 176 : Peter O'Toole, Marc Maron
- Episode 177 : Julianne Moore, Madonna, The Hold Steady
- Episode 178 : Kristin Chenoweth, John Witherspoon, Josh Ritter
- Episode 179 : Amy Sedaris, Jason Randal, America with Ryan Adams & Ben Kweller
- Episode 180 : Paul Newman, Sebastian Bourdais, Diana Ross
- Episode 181 : Tina Fey, Terri and Bindi Irwin
- Episode 182 : Harry Shearer, Vera Farmiga, Mat Kearney
- Episode 183 : Dan Rather, Tricia Helfer, Andy Kindler
- Episode 184 : Kevin Spacey, Alicia Keys, Nellie McKay & The Brooklyn Philharmonic
- Episode 185 : Ricky Gervais, Forest Whitaker, The Shins
- Episode 186 : Frank Caliendo, Mandy Moore, Rosanne Cash
- Episode 187 : Bill Murray, LeBron James
- Episode 188 : David Spade, Alexandra Pelosi, Dustin Kensrue
- Episode 189 : Dr. Phil McGraw, Fall Out Boy
- Episode 190 : Randy Jackson, Harry Connick Jr., Regis
- Episode 191 : Chris Elliott, Kelly Ripa, John Mellencamp
- Episode 192 : Jack Hanna, Katherine Heigl, Patty Griffin
- Episode 193 : Rachael Ray, Frank Caliendo, The Fab Faux
- Episode 194 : Drew Barrymore, Rickie Lee Jones, Kevin Johnson with Clyde & Matilda
- Episode 195 : Peyton Manning, Dan Horn with Orson, The Cat Empire
- Episode 196 : Martha Stewart, Otto Petersen with George, Norah Jones
- Episode 197 : Sienna Miller, NAS, Jim Barber with Seville
- Episode 98 : Tracy Morgan, Gabrielle Union, Brad Cummings and Rex
- Episode 99 : Jim Carrey, Daytona 500 winner Kevin Harvick
- Episode 100 : Barbara Walters, David Neeleman, K-os
- Episode 101 : Former President Bill Clinton, Patti Scialfa
- Episode 102 : Danny DeVito, Larry David, Avril Lavigne
- Episode 103 : Jessica Alba, George Saunders, The Manchester Orchestra
- Episode 104 : Rachael Ray, Frank Rich, Arctic Monkeys
- Episode 105 : Jodie Foster, Glen Hansard & Markéta Irglová
- Episode 106 : Dr. Phil McGraw, Andy Kindler, Suzanne Vega
- Episode 107 : Viggo Mortensen, Kat Von D, Daughtry, a Top Ten List presented by 10 NASCAR stars
- Episode 108 : Martha Stewart, Fred Willard, a Top Ten List presented by Billy Bob Thornton
- Episode 109 : Regis Philbin, Chamillionaire
- Episode 110 : Jamie Foxx, Jimmy Smits, Will.I.Am
- Episode 111 : Kate Walsh, Kevin Smith, Rascal Flatts
- Episode 112 : Jennifer Garner, Ken Burns, Chaka Khan
- Episode 113 : Stupid Human Tricks, Whoopi Goldberg, Melissa Etheridge
- Episode 114 : Paris Hilton, Emile Hirsch
- Episode 115 : Sean Penn, Barry Sonnenfeld, Ben Harper
- Episode 116 : Jude Law, Sarah Silverman, John Fogerty
- Episode 117 : Alec Baldwin, Faith Hill
- Episode 118 : Nicolette Sheridan, Tony Snow, Rihanna
- Episode 119 : Bob Newhart, Angela Kinsey, Iron and Wine
- Episode 120 : George Clooney, Kid Rock
- Episode 121 : Jennifer Lopez, Alan Greenspan
- Episode 122 : Stephen Colbert, Eva Mendes, Queens of the Stone Age
- Episode 123 : Anne Heche, Sue Johanson, Mariza
- Episode 124 : Halle Berry, Bill Hader, Spring Snake Symphony
- Episode 125 : Jake Gyllenhaal, Connie Britton, 50 Cent
- Episode 126 : Richard Simmons, Casey Affleck, Sondre Lerche
- Episode 127 : Rebecca Romijn, Jimmie Walker, LeAnn Rimes
- Episode 128 : Steve Carell, Chris Russo, Chris Elliott, Band of Horses
- Episode 129 : Amanda Peet, Patrick Warburton, Jeff Caldwell
- Episode 130 : Jerry Seinfeld, Joe Torre
- Episode 131 : Jennifer Connelly, Slash, Nicole Atkins
- Episode 132 : David Spade, Penn & Teller, Jonathan Papelbon
- Episode 133 : Dr. Phil McGraw, Ryan Adams
- Episode 134 : Bill Murray, Jay-Z
- Episode 135 : Robin Williams, Lupe Fiasco
- Episode 136 : Bill Maher, Ellen Page, the cast of Broadway's Young Frankenstein
- Episode 137 : Donald Trump, Shooter Jennings
- Episode 138 : Tom Hanks, Gov. Mike Huckabee
- Episode 139 : Lucy Liu, Alex Roy, MGMT
- Episode 140 : Morgan Freeman, Tom Brokaw, Chuck Prophet
- Episode 141 : Howard Stern, Ayo
- Episode 142 : Tracy Morgan, Kat Von D, Dropkick Murphys
- Episode 143 : Katie Holmes, Frank Caliendo, Maroon 5
- Episode 144 : Denzel Washington, Don Rickles
- Episode 145 : Michael Douglas, Katherine Heigl, Wyclef Jean
- Episode 146 : Sylvester Stallone, the Teutul family, the Mars Volta
- Episode 147 : Diane Keaton, Jim Gaffigan
- Episode 148 : Sarah Michelle Gellar, Dan Patrick, Ringo Starr
- Episode 149 : Sen. John Edwards, Diablo Cody, Josh Ritter, David Fathead Newman
- Episode 150 : Charles Grodin, New York Giant Lawrence Tynes, The Redwalls
- Episode 151 : Julia Louis-Dreyfus, T.J. Miller, Super Furry Animals
- Episode 152 : Nathan Lane, Jake Johannsen
- Episode 153 : Jessica Alba, Julie Chen, The Whigs
- Episode 154 : Bill Cosby, Lake Bell, The Matt Savage Trio
- Episode 155 : Dr. Phil McGraw, Lena Headey, Gary Allan
- Episode 156 : Stupid Human Tricks, Eva Longoria Parker, Colbie Caillat
- Episode 157 : Paris Hilton, Artie Lange, Vampire Weekend
- Episode 158 : Sen. Hillary Clinton, Sheryl Crow
- Episode 159 : Matthew McConaughey, Gary Mule Deer, Sheryl Crow
- Episode 160 : Eli Manning, Vince Vaughn, A Fine Frenzy
- Episode 161 : Kate Hudson, Jack Hanna
- Episode 162 : Colin Farrell, Blake Lively, Lenny Kravitz
- Episode 163 : Kate Walsh, Jason Sudeikis, OK Go and Bonerama
- Episode 164 : Evangeline Lilly, Marisa Miller, Brad Paisley
- Episode 165 : Martin Short, Amy Ryan
- Episode 166 : Regis Philbin, Joseph Arthur
- Episode 167 : Charles Barkley, Bill Burr
- Episode 168 : Dennis Quaid, Ryan Newman, Sharon Jones and the Dap-Kings
- Episode 169 : Randy Jackson, Saffron Burrows, Ray Davies
- Episode 170 : Amy Sedaris, Erika Jensen, Foo Fighters
- Episode 171 : Steve Martin, hand shadows performance with Raymond Crowe
- Episode 172 : Diddy, Al Lubel
- Episode 173 : Will Ferrell, Michael McDonald
- Episode 174 : Courteney Cox, Thomas Friedman, Chingy with Ludacris
- Episode 175 : Kid Scientists, Natalie Portman, Kenna
- Episode 176 : Amy Adams, Jamie Oliver, Liam Finn
- Episode 177 : Woody Harrelson, Tommy Tiernan
- Episode 178 : Jim Carrey, Paula Abdul
- Episode 179 : Martha Stewart, Snoop Dogg
- Episode 180 : Charlize Theron, Lewis Black, British Sea Power
- Episode 181 : Kate Beckinsale, Graham Colton
- Episode 182 : Jaime Pressly, Brian Regan
- Episode 183 : Rainn Wilson, Mike Golic & Mike Greenberg, Bell X1
- Episode 184 : Al Franken, Lauren Conrad, The Cribs
- Episode 185 : Brooke Shields, Seth Meyers, Gutter Twins
- Episode 186 : Demi Moore, Anthony Bourdain, Counting Crows
- Episode 187 : Kate Bosworth, John Witherspoon, The Raveonettes
- Episode 188 : Brian Williams, Judy Greer, Langhorne Slim
- Episode 189 : Helen Mirren, Jose Canseco
- Episode 190 : Sen. John McCain, Cat Power
- Episode 191 : George Clooney, Norah Jones
- Episode 192 : Renee Zellweger, Gayle King, Paddy Casey
- Episode 193 : Ellen Pompeo, Jay-Z, Mary J. Blige
- Episode 194 : Al Pacino, David Wright
- Episode 195 : Kelsey Grammer, Kristen Bell, Rogue Wave
- Episode 196 : Uma Thurman, Graham Rahal, The Gossip
- Episode 197 : Kelly Ripa, Dr. John P. Holdren, The Black Keys
- Episode 198 : Amy Poehler, Jason Segel, Jordan Zevon
- Episode 199 : Billy Crystal, Maria Sharapova
- Episode 100 : Helen Hunt, Chris Mad Dog Russo, Kathleen Edwards
- Episode 101 : Nicolas Cage, Anna Torv, Terrence Howard
- Episode 102 : Dr. Phil McGraw, Tilda Swinton, Tricky
- Episode 103 : Robin Williams, Shannen Doherty, Duffy
- Episode 104 : John Malkovich, Hayden Panettiere, Steve Earle
- Episode 105 : Keira Knightley, Thomas L. Friedman
- Episode 106 : Jada Pinkett Smith, Chris Russo, Michael Buble
- Episode 107 : Sen. Barack Obama, LeBron James
- Episode 108 : Jessica Simpson, Jack Hanna
- Episode 109 : Meg Ryan, Ricky Gervais
- Episode 110 : Bill Clinton, Chris Rock
- Episode 111 : Julianne Moore, Tom Dreesen & Tim Reid, Kings of Leon
- Episode 112 : Keith Olbermann, Chandra Wilson, Delta Goodrem
- Episode 113 : Paris Hilton, Usain Bolt, Morningwood
- Episode 114 : Lance Armstrong, Kristen Wiig, TV on the Radio
- Episode 115 : Julia Louis-Dreyfus, Michael Cera, Pete Seeger
- Episode 116 : Anne Hathaway, Josette Sheeran, The Virgins
- Episode 117 : Kate Walsh, Barry Sonnenfeld, Darius Rucker
- Episode 118 : Calista Flockhart, Bill Hader, Lucinda Williams
- Episode 119 : Brian Williams, Tim Robbins
- Episode 120 : Russell Crowe, Sarah Vowell, The Pretenders
- Episode 121 : Debra Messing, John Carter, Tegan & Sara
- Episode 122 : Dennis Quaid, Sarah Chalke, Buddy Guy
- Episode 123 : Bill Murray, Beck
- Episode 124 : Jeremy Piven, Elizabeth Banks, Lou Reed
- Episode 125 : Sarah Silverman, the Teutuls, Ra Ra Riot
- Episode 126 : Josh Brolin, Amy Sedaris, Blues Traveler
- Episode 127 : Martin Short, Marv Albert
- Episode 128 : Sen. John McCain, Ne-Yo
- Episode 129 : Tina Fey, Frank Caliendo, Tim Montana
- Episode 130 : Bill O'Reilly, Lauren Conrad
- Episode 131 : Regis Philbin, James Taylor
- Episode 132 : Alec Baldwin, Paul Mooney, Ryan Adams
- Episode 133 : Ashley Olsen, Paul Rudd, John Legend
- Episode 134 : Marcia Cross, Alan Zweibel
- Episode 135 : Paris Hilton, Elvis Costello, Jenny Lewis, a Top Ten List by Ricky Gervais
- Episode 136 : Tom Brokaw, Vera Farmiga
- Episode 137 : Ben Stiller, Q-Tip
- Episode 138 : Natalie Portman, Artie Lange, Brad Paisley
- Episode 139 : Ted Turner, Jamie Oliver, Taylor Swift
- Episode 140 : Don Rickles, Amy Brenneman, Alicia Keys
- Episode 141 : Russell Brand, Charlie Haden
- Episode 142 : Bruce Willis, Sia
- Episode 143 : Bill Cosby, Matt Braunger
- Episode 144 : Emma Thompson, Michelle Felicetta, Purple Reign
- Episode 145 : Carla Bruni Sarkozy, Jack Hanna, Cold Hard Cash
- Episode 146 : Katie Couric, Dev Patel, Mr. Brownstone
- Episode 147 : Stephen Colbert, Kristen Stewart, Super Diamond
- Episode 148 : James Franco, Bruce McCall, The Allstarz
- Episode 149 : Nicole Kidman, Simon Baker, Kanye West
- Episode 150 : Reese Witherspoon, Harry Connick Jr.
- Episode 151 : Teri Hatcher, Ludacris
- Episode 152 : Denis Leary, John Mayer
- Episode 153 : Tom Arnold, Faith Hill
- Episode 154 : Jennifer Connelly, Anderson Cooper, The Duke Spirit
- Episode 155 : Amy Adams, Michael Sheen, Jamey Johnson
- Episode 156 : Keanu Reeves, Paula Abdul, Loudon Wainwright III
- Episode 157 : Sen. John McCain, Bon Iver
- Episode 158 : Meryl Streep, Jeff Altman
- Episode 159 : Adam Sandler
- Episode 160 : Tom Cruise, Fall Out Boy
- Episode 161 : Jennifer Aniston, Broken Social Scene
- Episode 162 : Will Smith, Of Montreal
- Episode 163 : Jerry Seinfeld, Leona Lewis
- Episode 164 : Dustin Hoffman, Todd Rundgren
- Episode 165 : Jay Thomas, Mickey Rourke, Darlene Love
- Episode 166 : Tracy Morgan, Matt Braunger
- Episode 167 : Kate Hudson, Glasvegas
- Episode 168 : Kevin James, Becky Quick, Erin McCarley
- Episode 69 : Ricky Gervais, Rose Byrne, Okkervil River
- Episode 70 : Kate Winslet, Marv Albert
- Episode 71 : Kiefer Sutherland, Wendy Liebman
- Episode 72 : Billy Crystal, Kara DioGuardi
- Episode 73 : Salma Hayek, Jimmie Walker
- Episode 74 : Clint Eastwood, Randy Rogers Band
- Episode 75 : Kyra Sedgwick, Gwen Ifill
- Episode 76 : Zach Braff, Arj Barker, The Airborne Toxic Event
- Episode 77 : Brian Williams, Ben Kweller
- Episode 78 : Evangeline Lilly, Seth Meyers, Andrew Bird
- Episode 79 : Lauren Graham, Guy Fieri, MENEW
- Episode 80 : Renee Zellweger, Tony Dungy, Graham Nash sits in with the band
- Episode 81 : Mary Hicks, the Gaslight Anthem
- Episode 82 : Ben Roethlisberger, Steve Martin
- Episode 83 : Rod Blagojevich, Richard Jenkins
- Episode 84 : Joe Torre, Demetri Martin, Lyle Lovett and John Hiatt
- Episode 85 : Isla Fisher, extreme fisherman Matt Watson, Mark Olson and Gary Louris, a Top Ten List presented by Lil' Wayne
- Episode 86 : Dakota Fanning, Keith Alberstadt, Beirut
- Episode 87 : Naomi Watts, Danny McBride, 2009 Sports Illustrated Swimsuit Issue cover reveal
- Episode 88 : The crew of US Airways Miracle On The Hudson Flight 1549, Heartless Bastards
- Episode 89 : Joaquin Phoenix, Bar Refaeli, Anthony Hamilton
- Episode 90 : Chris Russo, the Jonas Brothers, Ashford & Simpson
- Episode 91 : Martha Stewart, Jake Johannsen, Matt Nathanson
- Episode 92 : Ellen Pompeo, Daytona 500 winner Matt Kenseth, Willie Nelson with Asleep at the Wheel
- Episode 93 : Bonnie Hunt, M. Ward
- Episode 94 : Donald Trump, Antony and the Johnsons
- Episode 95 : David Spade, Jeffrey Sachs, David Sanborn with Sam Moore
- Episode 96 : Barbara Walters, Mike Birbiglia, Shemekia Copeland
- Episode 97 : Katie Couric, U2
- Episode 98 : Felicity Huffman, Artie Lange, U2
- Episode 99 : Dr. Phil McGraw, U2
- Episode 100 : Jon Stewart, U2, a Top Ten List featuring 10 Team USA members from the World Baseball Classic
- Episode 101 : Howie Mandel, Dock Diving Dogs, Dirty Projectors
- Episode 102 : Jeremy Piven, Rumer Willis, Black Crowes
- Episode 103 : Jason Bateman and White House official Dr. John P. Holdren
- Episode 104 : Billy Crystal and John Fogerty
- Episode 105 : Neil Patrick Harris, Steve Mazan, Edward Sharpe & The Magnetic Zeros
- Episode 106 : Tony Blair and Julianna Margulies
- Episode 107 : Jay-Z, Martha Stewart, and George Jones
- Episode 108 : Matt Damon and Jack Hanna
- Episode 109 : Michael Douglas, Leighton Meester, and Kid Cudi
- Episode 110 : President Barack Obama
- Episode 111 : Former President Bill Clinton and LeBron James
- Episode 112 : Simon Baker and Mary J. Blige
- Episode 113 : Craig Ferguson, Kristin Chenoweth, and Snow Patrol
- Episode 114 : Bruce Willis, LL Cool J, and The Noisettes
- Episode 115 : Felicity Huffman, Dr. Mehmet Oz, and The Avett Brothers
- Episode 116 : Kelsey Grammer, Alyson Hannigan, and Miranda Lambert
- Episode 117 : Madonna and Harry Connick Jr.
- Episode 118 : Woody Harrelson and Kim Kardashian
- Episode 119 : Larry David, Olivia Wilde and Tom Russell
- Episode 120 : Steve Martin and Lea Michele
- Episode 121 : CBS Orchestra bandleader Paul Shaffer, Eliza Dushku and KISS
- Episode 122 : Vince Vaughn, Carey Mulligan, and Rosanne Cash
- Episode 123 : Kristin Davis and Barry Sonnenfeld
- Episode 124 : Jon Hamm, Andy Kindler, and Brett Dennen
- Episode 125 : Garry Shandling, Kaley Cuoco, and Tim McGraw
- Episode 126 : Sienna Miller, Aziz Ansari, and Dead By Sunrise
- Episode 127 : Tina Fey, Chris Russo, and Mika
- Episode 128 : Don Rickles and Built To Spill
- Episode 129 : Uma Thurman and Tim McGraw
- Episode 130 : Charles Barkley, Cheryl Hines, Harper Simon
- Episode 131 : Courteney Cox, William Knoedelseder, Florence and the Machine
- Episode 132 : Patrick Dempsey, Bud Selig, Sting
- Episode 133 : Tom Hanks, Weezer, a Top Ten List presented by Chad Ochocinco
- Episode 134 : Regis Philbin, Brian Regan, Weezer
- Episode 135 : Julia Louis-Dreyfus, Guy Fieri, Carrie Underwood, Top Ten with Meb Keflezighi
- Episode 136 : Al Gore, Brad Paisley, a Top Ten List presented by Michael Bublé
- Episode 137 : Bill Cosby, Ryan Bingham
- Episode 138 : Derek Jeter, Jorge Posada & Andy Pettitte, Bill Maher, Keith Urban
- Episode 139 : Ricky Gervais, Brian Regan, Ralph Stanley and the Clinch Mountain Boys
- Episode 140 : Bill Murray, Gabourey “Gabby” Sidibe
- Episode 141 : Jack Hanna, Shakira
- Episode 142 : Kate Walsh, Norah Jones
- Episode 143 : Kid Scientists, Amanda Peet, the Cribs with Johnny Marr
- Episode 144 : Mariah Carey, Kumail Nanjiani
- Episode 145 : Sharon Stone, Seth Meyers, Wyclef Jean and Cyndi Lauper
- Episode 146 : Penelope Cruz, Joe Cada, The Script
- Episode 147 : Robert Pattinson, Ray Davies
- Episode 148 : Stephen Colbert, Emily Blunt, John Mayer
- Episode 149 : Viggo Mortensen, Paula Poundstone, and Lyle Lovett
- Episode 150 : Robin Williams, Ashley Greene
- Episode 151 : Zac Efron, Carrie Fisher, Rihanna
- Episode 152 : Natalie Portman, Adam Lambert
- Episode 153 : Ray Romano, Anna Kendrick
- Episode 154 : Barbara Walters, Blakroc
- Episode 155 : Rachel Weisz, Rob Thomas
- Episode 156 : Kate Hudson, Dr. James Hansen, Tori Amos
- Episode 157 : Kyra Sedgwick, Brian Scott McFadden, Joe Perry
- Episode 158 : Hugh Grant, Zoe Saldana, Alicia Keys
- Episode 159 : Sarah Jessica Parker, Leona Lewis
- Episode 160 : Robert Downey Jr, Martin Short, and Kris Allen
- Episode 161 : Shannon Eis, Jude Law, and Matisyahu
- Episode 162 : Tobey Maguire, Tom Dreesen, and Alicia Keys
- Episode 163 : Maggie Gyllenhaal and John Witherspoon
- Episode 164 : Susan Sarandon, Colbie Caillat
- Episode 165 : Alec Baldwin, Jay Thomas, Darlene Love
- Episode 166 : Michael Cera, Jenna Elfman, David Gray
- Episode 167 : Amy Adams, Zachary Levi, Vampire Weekend
- Episode 168 : Sigourney Weaver, Marv Albert, Julian Casablancas
- Episode 169 : Bradley Cooper, Rachel Maddow, Nick Jonas
- Episode 170 : Teri Hatcher, Jake Johannsen, The Dodos
- Episode 171 : Sacha Baron Cohen, Joel McHale
- Episode 172 : Whoopi Goldberg, Jason Sudeikis, Findlay Brown
- Episode 173 : Kiefer Sutherland, Keri Russell, The Hotrats
- Episode 174 : Denzel Washington, Dr. O. Wayne Isom, The Low Anthem
- Episode 175 : Glenn Close, Eddie Brill, Matt Morris
- Episode 176 : Kristen Bell, Randy Jackson, The Heavy
- Episode 177 : Dwayne Johnson, Bettina Luescher, The Swell Season
- Episode 178 : Claire Danes, Will Arnett, James Taylor, Carole King
- Episode 179 : Harrison Ford, Lou Reed, Blind Boys of Alabama
- Episode 180 : Catherine Zeta-Jones, Jeff Stilson, Charlotte Gainsbourg
- Episode 181 : Bruce Willis, Ne-Yo
- Episode 182 : John Travolta, Shaun White, Ben Harper & Relentless7
- Episode 183 : Sarah Silverman, Jeremy Renner, Nneka, a Top Ten List presented by Paris Hilton
- Episode 184 : Jamie Foxx, Amanda Seyfried, Robin Thicke
- Episode 185 : Jack Hanna, Joe Wong, the Swell Season
- Episode 186 : Drew Brees, Sandra Bullock, Josh Turner
- Episode 187 : Jennifer Garner, the Sports Illustrated swimsuit issue cover model, Sade
- Episode 188 : Jessica Biel, Christoph Waltz
- Episode 189 : Regis and Joy Philbin, a Top Ten List presented by Benicio Del Toro
- Episode 190 : Jeff Bridges, Joe Wong, the Soft Pack
- Episode 191 : Tracy Morgan, the Daytona 500 winner, Fanfarlo
- Episode 192 : Ben Kingsley, Mary J. Blige
- Episode 194 : Scarlett Johansson, Daniel Merriweather
- Episode 195 : Nicole Richie, comic Tom Papa.
- Episode 196 : Bill Murray, Ludacris
- Episode 197 : Mitt Romney, Mia Wasikowska
- Episode 198 : Jerry Seinfeld, Tom Brokaw
- Episode 199 : Tom Hanks, Spoon
- Episode 200 : Matt Damon, Danny Bhoy, Corinne Bailey Rae
- Episode 101 : Brian Williams, Paula Abdul
- Episode 102 : Tim McGraw, Shaquille O'Neal, Keri Hilson
- Episode 103 : Jennifer Connelly, Dr. Oz, Justin Townes Earle
- Episode 104 : Seth Rogen, Beau Garrett, the Walkmen
- Episode 105 : Regis Philbin, Hannibal Buress, No Age
- Episode 106 : Bill Cosby, a Top Ten List presented by Nicole Snooki Polizzi, the Black Keys
- Episode 107 : Vince Vaughn, Mike Wolfe & Frank Fritz, Cage the Elephant
- Episode 108 : Kevin James, Olivia Munn, The Low Anthem
- Episode 109 : Kelsey Grammer, Amar'e Stoudemire, Gregg Allman
- Episode 110 : Joan Rivers, Jeff Caldwell, Wintersleep
- Episode 111 : Jack Hanna, Steven Tyler
- Episode 112 : Betty White, Kim & Kourtney Kardashian, the Script
- Episode 113 : Martin Short, Greta Gerwig, Darius Rucker
- Episode 114 : Kaley Cuoco, Piers Morgan, Wanda Jackson, Miss Arkansas, Alyse Eady
- Episode 115 : Nathan Lane, Mike Palascak, Esperanza Spalding
- Episode 116 : Justin Bieber, Pauley Perrette, Best Coast
- Episode 117 : Matthew Perry, Chris Elliott, Top Ten with Mitt Romney, the National
- Episode 118 : Kate Walsh, Jim Gaffigan, Boxer Rebellion
- Episode 119 : Howard Stern, Naughty By Nature
- Episode 120 : Martha Stewart, Top Ten with Justin Bieber, Robert Plant
- Episode 121 : Super Bowl MVP Aaron Rodgers, Martin Lawrence, Steel Magnolia
- Episode 122 : Adam Sandler, Chris Colfer, Gang of Four
- Episode 123 : Anderson Cooper, Elton John
- Episode 124 : Nicole Snooki Polizzi, Judah Friedlander, Bryan Ferry
- Episode 125 : Ed Helms, Ted Alexandro, Steel Magnolia
- Episode 126 : S.I. Swimsuit Cover Reveal & Top 10, Tom Brokaw, Theophilus London
- Episode 127 : Forest Whitaker, S.I. Swimsuit Cover Model Irina, Josh Groban, Top Ten with Joy Philbin
- Episode 128 : Bill Hader, Grocery Bagging Champ Krystal, Amos Lee
- Episode 129 : Paris Hilton, Nathan Fillion, Scissor Sisters
- Episode 130 : David Spade, Andy Kindler, Lukas Nelson and Promise of the Real
- Episode 131 : Donald Rumsfeld, Cobie Smulders
- Episode 132 : Amy Poehler, Jean Chu and Dusty the Cat, Deerhunter
- Episode 133 : Rainn Wilson, Hank Aaron
- Episode 134 : Senator Rand Paul, Bright Eyes
- Episode 135 : Matthew Morrison, Jeff Altman, Jessica Lea Mayfield
- Episode 136 : Brian Williams, Trey Parker & Matt Stone, Zac Brown Band
- Episode 137 : Amanda Seyfried, B.J. Novak
- Episode 138 : Donald Trump, Vanessa Hudgens, Oh Land
- Episode 139 : Robin Williams, Judy Greer
- Episode 140 : Charles Barkley, Sarah Vowell, Cold War Kids
- Episode 141 : Bradley Cooper, Mindy Kaling, Bob Geldof
- Episode 142 : Steve Martin, Selena Gomez
- Episode 143 : Dana Carvey, Dr. Michio Kaku, British Sea Power
- Episode 144 : Katie Couric, The Pains of Being Pure at Heart
- Episode 145 : Ben Stiller, Dario Franchitti, The Strokes
- Episode 146 : Jungle Jack Hanna, Danny McBride
- Episode 147 : Regis Philbin, Snoop Dogg
- Episode 148 : Norm Macdonald, CC Sabathia, Willie Nelson, Norah Jones and Wynton Marsalis
- Episode 149 : Chris Rock, Ellen Page, Funeral Party
- Episode 150 : James Franco, Royal Bangs
- Episode 151 : Jennifer Garner, Jamie Oliver, Robbie Robertson
- Episode 152 : Don Rickles, Eva Longoria
- Episode 153 : Alec Baldwin, Wiz Khalifa
- Episode 154 : Ricky Gervais, Top Ten with Katie Holmes, Foo Fighters
- Episode 155 : Courteney Cox, Aziz Ansari, Alison Krauss & Union Station featuring Jerry Douglas
- Episode 156 : Seth Meyers, Carmelo Anthony, TV on the Radio
- Episode 157 : Tina Fey, Tommy Johnagin, The Gaslight Anthem
- Episode 158 : Bill Maher, Cote de Pablo, Lupe Fiasco
- Episode 159 : Will Ferrell, The Twilight Singers
- Episode 160 : Kate Hudson, Rich Eisen, Emmylou Harris
- Episode 161 : Dr. Phil McGraw, Chris Hemsworth, Broadway musical Catch Me If You Can
- Episode 162 : John Krasinski, Brian Kiley, Steve Earle
- Episode 163 : Brian Williams, Rex Ryan
- Episode 164 : Caroline Kennedy, Ty Burrell
- Episode 165 : Betty White, Rick Harrison, Morning Teleportation
- Episode 166 : Jodie Foster, Tom Dreesen, Neon Trees
- Episode 167 : Bill Murray, ''The Human Fuse'' Brian Miser, Brother
- Episode 168 : Albert Brooks, Kristen Wiig
- Episode 169 : Mark Harmon, Chris Morgan, Hugo
- Episode 170 : Kyra Sedgwick, Bret Michaels, Jimmy Cliff
- Episode 171 : Stupid human tricks, Jim Parsons, Manchester Orchestra
- Episode 172 : Joan Rivers, Nick Griffin, Okkervil River
- Episode 173 : Julianna Margulies, Andy Cohen, a Top Ten List presented by Christina Aguilera, White Lies
- Episode 174 : Martin Short, Melissa McCarthy, Tinie Tempah
- Episode 175 : Keith Olbermann, Julie Bowen, Ben Harper
- Episode 176 : Kelly Ripa, Jennifer Lawrence, How to Succeed in Business Without Really Trying
- Episode 177 : Tracy Morgan, Jake Johannsen, The Airborne Toxic Event
- Episode 178 : Lady Gaga, Eric Stonestreet, The Vaccines
- Episode 179 : Ewan McGregor, Scott Pelley, Brad Paisley
- Episode 180 : Piedmont Bird Callers, Kevin Bacon, Augustana
- Episode 181 : Ray Romano, Reese Waters, Arctic Monkeys
- Episode 182 : Meredith Vieira, Indianapolis 500 winner Dan Wheldon, Drum Solo Week kicks off with Anton Fig
- Episode 183 : Kyle Chandler, Kathy Griffin, Sheila E.
- Episode 184 : Jon Cryer, Rachel Maddow, Roy Haynes
- Episode 185 : Neil Patrick Harris, Mike Birbiglia, Neil Peart
- Episode 186 : Adm. Michael Mullen, Top Ten by Betty White, Black Joe Lewis & the Honeybears
- Episode 187 : Ryan Reynolds, chef Eric Ripert and the cast of the Broadway musical Anything Goes
- Episode 188 : Jim Carrey, Rosie Huntington-Whiteley, Todd Rundgren
- Episode 189 : Samuel L. Jackson, Texas Ranger Josh Hamilton, Jennifer Hudson
- Episode 190 : Cameron Diaz, Eddie Vedder
- Episode 91 : Jason Bateman, Amy Sedaris, Top Ten by Keith Olbermann, Drive-By Truckers
- Episode 92 : Kevin James, pet fashion designer Ada Nieves, Beady Eye
- Episode 93 : Jason Segel, horse whisperer Buck Brannaman, Noah and the Whale
- Episode 94 : Shia LaBeouf, Bert Kreischer, Dawes
- Episode 95 : Tom Hanks, Sleepy Man Banjo Boys
- Episode 96 : Patrick Dempsey, Erica Hill, Marty Stuart
- Episode 97 : Julia Roberts, Cake
- Episode 98 : Emma Watson, George Lopez, Incubus
- Episode 99 : Roseanne Barr, Tom Felton, Blake Shelton
- Episode 100 : Ryan Gosling, Gomez
- Episode 1 : Will Arnett, Lisa Lampanelli, Guided by Voices
- Episode 2 : Brian Williams, WU LYF
- Episode 3 : Tina Fey, Jeremy Irvine, Barr Brothers
- Episode 4 : Kristen Bell, Dan Naturman, Blind Pilot
- Episode 5 : Mark Wahlberg, Heather Morris, Snow Patrol
- Episode 6 : Kate Beckinsale, Marv Albert, The Little Willies
- Episode 7 : Dolly Parton, Alan Zweibel
- Episode 8 : Sen. John McCain, Johnny Winter
- Episode 9 : Viggo Mortensen, Dennis Regan, Tony Bennett
- Episode 10 : Simon Baker, Elizabeth Banks, Seal
- Episode 11 : Ricky Gervais, Jessica Chastain, Kathleen Edwards
- Episode 12 : Marg Helgenberger, Michael Fassbender, Ellie Goulding
- Episode 13 : Kathy Griffin, Simon Helberg, Joseph Arthur
- Episode 14 : Dana Carvey, Jon Fisch, Los Campesinos!
- Episode 15 : Jennifer Lopez, Rob Schneider, James McCartney
- Episode 16 : Bill Murray, Girls' Generation
- Episode 17 : Howard Stern, The Airborne Toxic Event
- Episode 18 : Woody Harrelson, Stephen Merchant, Lana Del Rey
- Episode 19 : Michelle Williams, Jake Johannsen, Ziggy Marley
- Episode 20 : Eli Manning, Sarah Michelle Gellar, Die Antwoord
- Episode 21 : Denzel Washington, The Fray
- Episode 22 : Ryan Reynolds, Ellie Kemper, Dierks Bentley
- Episode 23 : Nicolas Cage, Michelle Dockery, The Kills
- Episode 24 : David Spade, Betty Wright
- Episode 25 : Reese Witherspoon, Michael Weatherly, Top Ten by Sports Illustrated Swimsuit models, Kasabian
- Episode 26 : Viola Davis, the 2012 Sports Illustrated Swimsuit cover model, Mark Ronson, Erykah Badu, The Dap-Kings, Zigaboo Modeliste
- Episode 27 : Jon Stewart, American Bagging Champion Stephanie Teteak, Yelawolf with Kid Rock
- Episode 28 : Joan Rivers, Andrew Lincoln, Jason Mraz
- Episode 29 : Kristen Wiig, Mike Birbiglia, Butch Walker and the Black Widows
- Episode 30 : Jack Hanna, Jesse Tyler Ferguson
- Episode 31 : Alec Baldwin, Eric Hutchinson
- Episode 32 : Paul Rudd, John Witherspoon, Heartless Bastards
- Episode 33 : Kristin Chenoweth, Joe Scarborough, K'naan featuring Nelly Furtado
- Episode 34 : Matthew Broderick, Nick Griffin, We Are Augustines
- Episode 35 : Ed Helms, Dan Patrick, Lyle Lovett
- Episode 36 : Nathan Lane, Pauley Perrette, Estelle
- Episode 37 : Neil Patrick Harris, Taylor Kitsch, Robert Glasper Experiment featuring Lupe Fiasco & Bilal
- Episode 38 : Jon Hamm, Ted Alexandro, White Rabbits
- Episode 39 : Will Ferrell, Jon Bernthal
- Episode 40 : Amanda Peet, Nick Offerman, Top Ten by Cee-Lo Green, The Chieftains with the Low Anthem
- Episode 41 : Martin Short, The Ting Tings
- Episode 42 : Michelle Obama, Esperanza Spalding
- Episode 43 : Jennifer Lawrence, Gail Collins, The Shins
- Episode 44 : Debra Messing, Josh Hutcherson, Oberhofer
- Episode 45 : Rachel Maddow, Timothy Olyphant, Train
- Episode 46 : Jason Sudeikis, Lionel Richie, Jason Aldean
- Episode 47 : Chris Elliott, Mohamed Nasheed, Justin Townes Earle
- Episode 48 : Tracy Morgan, Jim Rome, The Broadway musical 'Once'
- Episode 49 : Megan Mullally, Joe Wong, Band of Skulls
- Episode 50 : Keith Olbermann, Allison Williams, Lukas Nelson & Promise of the Real
- Episode 51 : Kiefer Sutherland, Eugene Levy, The Punch Brothers
- Episode 52 : Ricky Gervais, Cobie Smulders, Tennis
- Episode 53 : Sean Hayes, Shooter Jennings
- Episode 54 : Magic Johnson, Larry Bird, Jim Gaffigan, Kaiser Chiefs
- Episode 55 : Billy Crystal, Alabama Shakes
- Episode 56 : Julia Louis-Dreyfus, Keith Alberstadt, Bonnie Raitt
- Episode 57 : Jason Segel, Zach Wahls, Fun
- Episode 58 : Amy Poehler, Wendy Williams, Trampled by Turtles
- Episode 59 : Rob Lowe, Gov. Brian Schweitzer, The War on Drugs
- Episode 60 : Robin Williams, Andrew Luck
- Episode 61 : Madden NFL 13 Cover Calvin Johnson, Chris Hemsworth, Darrell Hammond, Miike Snow
- Episode 62 : Don Rickles, Carrie Underwood
- Episode 63 : Seth Meyers, Krysten Ritter, Father John Misty
- Episode 64 : Stupid Pet Tricks, Johnny Galecki, Norah Jones
- Episode 65 : Stephen Colbert, Chloe Grace Moretz, The cast of 'Nice Work If You Can Get It'
- Episode 66 : Anderson Cooper, Yves Rossy, Electric Guest
- Episode 67 : Dr. Phil McGraw, Beth Behrs, Spiritualized
- Episode 68 : Jim Parsons, Mika Brzezinski, Macy Gray
- Episode 69 : Eva Longoria, Tom Dreesen, Florence and The Machine
- Episode 70 : Kid Scientists, Elizabeth Banks, Edward Sharpe & The Magnetic Zeros
- Episode 71 : Jon Cryer, Tommy Johnagin, M. Ward
- Episode 72 : Kelly Ripa, Adam Scott, Tenacious D
- Episode 73 : Brian Williams, El-P
- Episode 74 : Betty White, Moses Maddox, Best Coast
- Episode 75 : Conan O'Brien, Regina Spektor, John Mayer
- Episode 76 : Sacha Baron Cohen, Julie Chen, Beach House
- Episode 77 : Lea Michele, Barry Sonnenfeld, Shaolin Warriors of Ringling Bros
- Episode 78 : Will Smith, Gossip
- Episode 79 : Piedmont Bird Callers, Bill O'Reilly, Pitbull
- Episode 80 : Joan Rivers, Dario Franchitti, Silversun Pickups
- Episode 81 : Neil Patrick Harris, Noomi Rapace, Alan Jackson
- Episode 82 : Jane Fonda, Mayor of London Boris Johnson, Jimmy Cliff
- Episode 83 : Bill Murray, The Temper Trap
- Episode 84 : Mark Wahlberg, Sebastian Vettel, Black Box Revelation
- Episode 85 : Jack Hanna, Patti Smith
- Episode 86 : Adam Sandler, Jerry Douglas
- Episode 87 : Regis Philbin, Lenny Marcus, Elizabeth Cook
- Episode 88 : Denis Leary, Olivia Wilde, The Pierces
- Episode 89 : Jeff Daniels, Benjamin Walker, Walk the Moon
- Episode 90 : Alec Baldwin, Michael Kiwanuka
- Episode 91 : Justin Bieber, Michael Ian Black
- Episode 92 : Emma Stone, Jimmie Walker, Diamond Rugs
- Episode 93 : LeBron James, Andrew Garfield, Maroon 5
- Episode 94 : Channing Tatum, Scott Pelley, The Gaslight Anthem
- Episode 95 : Blake Lively, Drew Brees
- Episode 96 : Ray Romano, Tom Waits, Top Ten by American League All-Stars
- Episode 97 : Queen Latifah, Fred Armisen, Cory Chisel and the Wandering Sons
- Episode 98 : Bryan Cranston, R.A. Dickey, Zac Brown Band
- Episode 99 : Anne Hathaway, Moody McCarthy, Loudon Wainwright III
- Episode 100 : Morgan Freeman, Gallagher, Nas
- Episode 101 : Kathy Griffin; Chris Pratt; Big Boi
- Episode 102 : Regis Philbin; Zedd
- Episode 103 : Tracy Morgan; Marv Albert; Everest
- Episode 104 : Michael Strahan; Jessica Chastain; Conor Maynard
- Episode 105 : Brian Williams; Morrissey
- Episode 106 : Josh Brolin; Kathryn Bigelow; Ray Wylie Hubbard
- Episode 107 : Michael J. Fox; Lena Dunham
- Episode 108 : Catherine Zeta-Jones; Allison Williams; Jon Spencer Blues Explosion
- Episode 109 : Charlie Sheen; Phil Simms; José James
- Episode 110 : Jennifer Lawrence; Alan Zweibel; A$AP Rocky
- Episode 111 : Kim & Kourtney Kardashian; Buddy Guy
- Episode 112 : Jeremy Renner; Jack Hanna
- Episode 31 :
- Episode 32 : Johnny Depp; Bill Carter and The Blame
- Episode 33 : Luke Wilson; Dan Mintz; Imagine Dragons
- Episode 34 : Alec Baldwin; Emmylou Harris with Rodney Crowell
- Episode 35 : Joan Rivers; Jimmie Johnson; Kendrick Lamar
- Episode 36 : Tina Fey; Jesse Tyler Ferguson; Solange
- Episode 37 : Michael Bloomberg; Depeche Mode
- Episode 38 : Steve Carell; Emilia Clarke; Josh Ritter
- Episode 39 : Jim Carrey; Richard Thompson
- Episode 40 : Gerard Butler; Elizabeth Cook
- Episode 41 : Seth Meyers; Demetri Martin; Dropkick Murphys
- Episode 42 : Selena Gomez; Bob Sarlatte; Killer Mike
- Episode 43 : Bill Cosby; Mikaela Shiffrin; Garbage
- Episode 44 : Eva Mendes; Andy Hendrickson; The Airborne Toxic Event
- Episode 45 : James Franco; Andrew Borracchini; Ed Sheeran
- Episode 46 : Brian Williams; Pegi Young & The Survivors
- Episode 47 : Gary Gulman; Wavves
- Episode 48 : Shia LaBeouf; Jeff Altman; The Band Perry
- Episode 49 : Regis Philbin; Broadway musical “Rodgers & Hammerstein's Cinderella”
- Episode 50 : Louis C.K.; Rachel Maddow; The Flaming Lips
- Episode 51 : Martin Short; Tyler, the Creator
- Episode 52 : Chelsea Handler; Ross Bennett; Yeah Yeah Yeahs
- Episode 53 : Lindsay Lohan; Pete Lee; Gary Clark Jr.
- Episode 54 : Harrison Ford; Rita Wilson; Jake Bugg
- Episode 55 : Matthew McConaughey; Ryan Lochte; Steve Earle & The Dukes (& Duchess)
- Episode 56 : Steve Martin; Edie Brickell; Jenna Fischer
- Episode 57 : Kate Hudson; A.J. Clemente; Selena Gomez
- Episode 58 : Jim Parsons; Snoop Lion
- Episode 59 : Jon Hamm; Ricky Jay; The So So Glos
- Episode 60 : Mindy Kaling; Nada Bakos; Ben Harper with Charlie Musselwhite
- Episode 61 : Dr. Phil McGraw; Chris O'Dowd; Phoenix
- Episode 62 : Tobey Maguire; Tom Odell
- Episode 63 : Paris Hilton; Miriam Tucker; Atlas Genius
- Episode 64 : Nathan Lane; Joe Matarese; Kacey Musgraves
- Episode 65 : John Krasinski; Kerry Washington; James Blake
- Episode 66 : Zooey Deschanel; Jim Gaffigan; Pistol Annies; Todd Rundgren
- Episode 67 : Michael Strahan; Alyson Hannigan; Natalie Maines
- Episode 68 : Jack Hanna; Benedict Cumberbatch
- Episode 69 : Chris Pine; Tom Dreesen; She & Him
- Episode 70 : Mark Harmon; Amy Schumer; Luke Bryan
- Episode 71 : Tom Hanks; cast of “Pippin”
- Episode 72 : Ed Helms; Hoda Kotb; Brad Paisley
- Episode 73 : Barbara Walters; Jesse Eisenberg; MS MR
- Episode 74 : Will Arnett; Trevor Noah; Kurt Vile
- Episode 75 : Will Smith; The National
- Episode 76 : Jason Bateman; Piedmont bird callers; John Fogerty
- Episode 77 : Woody Harrelson; Tommy Johnagin; John Fogerty with Dawes
- Episode 78 : Neil Patrick Harris; Tony Kanaan; Frank Turner
- Episode 79 : Nathan Fillion; John Oliver; Local Natives
- Episode 80 : Johnny Galecki; John Mellencamp & Stephen King; Queens of the Stone Age
- Episode 81 : Vince Vaughn; Andy Kindler; Queens of the Stone Age
- Episode 82 : Russell Brand; Michael Shannon; Haim
- Episode 83 : Dana Carvey; Nick Robinson; cast of “Matilda”
- Episode 84 : Tom Brokaw; Darlene Love
- Episode 85 : Harry Connick, Jr.; Dylan Moran
- Episode 86 : Bill O'Reilly; Greta Gerwig; Quadron
- Episode 87 : Don Rickles; Nick Cannon; Tom Keifer
- Episode 88 : Jeff Daniels; Ken Jeong; Jim James
- Episode 89 : John Travolta; Chris DiStefano; Japandroids
- Episode 90 : Melissa McCarthy; Idris Elba; Dale Watson and His Lone Stars
- Episode 91 : Channing Tatum; Tim DeChristopher; Fitz and The Tantrums
- Episode 92 : Jamie Foxx; Patrick Kane; Wale
- Episode 93 : Johnny Depp; Marc Maron; Dawes
- Episode 94 : Michael Cera; Martha Stewart; Ra Ra Riot
- Episode 95 : Adam Sandler; Joseph Arthur
- Episode 96 : Salma Hayek Pinault; Tony Hale; Houndmouth
- Episode 97 : Kevin James; Shaun White; Darius Rucker
- Episode 98 : Bruce Willis; Bud Selig; Valerie Simpson
- Episode 99 : Bill Maher; Poppy Montgomery; Pokey LaFarge
- Episode 100 : Brian Williams; Court Yard Hounds
- Episode 101 : Lena Dunham; Max Greenfield; Brandy Clark
- Episode 102 : Joel McHale; Marv Albert; Washed Out
- Episode 103 : Scarlett Johansson; John Grant
- Episode 104 : Anderson Cooper; Bobby Moynihan; Will Hoge
- Episode 105 : Mindy Kaling; Jeff Altman; Red Fang
- Episode 106 : Bill Cosby; Sleigh Bells
- Episode 107 : Michael Strahan; Jennifer Nettles
- Episode 108 : Kevin Hart; Mo Rocca; The Orwells
- Episode 109 : Brian Williams; Rosanne Cash
- Episode 110 : Don Cheadle; Myq Kaplan; Roadkill Ghost Choir
- Episode 111 : Andy Samberg; Michael B. Jordan; Ellie Goulding
- Episode 112 : Martin Scorsese; Allison Williams; Cults
- Episode 113 : Rachel Maddow; Spike Jonze; No Age
- Episode 114 : Kevin Bacon; Pat McGann; Devon Avenue
- Episode 115 : Louis C.K.; B.J. Ganem; Artic Monkeys
- Episode 116 : Eric Stonestreet; Nick Goepper; Bastille
- Episode 117 : Drew Brees; B.J. Novak; Against Me!
- Episode 118 : Dr. Phil McGraw; Danny Koker; Dum Dum Girls
- Episode 119 : Bill Murray; Eagulls
- Episode 120 : Will Arnett; Broken Bells
- Episode 121 : George Clooney; Sting
- Episode 122 : Matt Damon; Lenny Kravitz
- Episode 123 : Patrick Stewart; The Flaming Lips
- Episode 124 : Regis Philbin; Ms. Lauryn Hill
- Episode 125 : Kevin Spacey, Amber Heard, a Top Ten List presented by the cast of
- Episode 126 : Sage Kotsenburg, Kate Mara
- Episode 127 : Kaitlyn Farrington, Lupita Nyong'o, Little Dragon
- Episode 128 : Keri Russell, Terry Fator
- Episode 129 : Pauley Perrette, Jeff Caldwell, Lake Street Dive
- Episode 130 : Kaley Cuoco-Sweeting, Dale Earnhardt, Jr., The Fray
- Episode 131 : Olympic Gold Medalist Ted Ligety, Kat Dennings, Lo-Fang
- Episode 132 : Meredith Vieira, Band of Horses
- Episode 133 : Stupid Human Tricks, Simon Helberg, Young the Giant
- Episode 134 : Jack (Jungle) Hanna, Jake Johannsen
- Episode 135 : Zach Braff, Sgt. Brendan Marrocco & Dr. Andrew Lee, Future Islands
- Episode 136 : Michael Keaton, Phantogram
- Episode 137 : Tom Selleck, Carrie Brownstein, David Nail
- Episode 138 : Tom Brokaw, Andrew Hadlock, Bob Mould
- Episode 139 : Mary-Louise Parker, Lenny Marcus, Joan Jett & the Blackhearts
- Episode 140 : Sen. John McCain, Little Mix
- Episode 141 : Jason Bateman, Miles Teller, Gary Allan
- Episode 142 : Sylvester Stallone, Theo James, Ledisi
- Episode 143 : Bryan Cranston, Melissa Rauch, Le1f
- Episode 144 : Bill O'Reilly, Nick Griffin, the Dough Rollers
- Episode 145 : Jimmy Carter
- Episode 146 : Emma Watson, Nick Offerman, a musical tribute to Johnny Cash
- Episode 147 : Peter Dinklage, Hari Kondabolu, Sage the Gemini
- Episode 148 : Cobie Smulders, Nick Cannon, Manchester Orchestra
- Episode 149 : Kristin Chenoweth, Amy Schumer, Johnnyswim
- Episode 150 : Bill Murray, Martha Stewart, Lady Gaga
- Episode 151 : Johnny Depp, Kevin Drew
- Episode 152 : Billy Crystal, Tony Hale, Liv Warfield
- Episode 153 : Rob Lowe, Brooklyn Decker, London Grammar
- Episode 154 : Lindsay Lohan, Jamie Edwards, Real Estate
- Episode 155 : Courteney Cox, Jimmie 'J.J.' Walker, Christina Perri
- Episode 156 : Stephen Colbert, Robin Roberts, Kelis
- Episode 157 : Sally Field, Timothy Simons, Needtobreathe
- Episode 158 : Neil Patrick Harris, Sarah Hyland, Ray LaMontagne
- Episode 159 : Piedmont Bird Callers, Michael J. Fox, Naughty Boy
- Episode 160 : Joel McHale, Vera Farmiga, Aloe Blacc
- Episode 161 : Lucy Liu, Ziggy Marley
- Episode 162 : Kiefer Sutherland, Adam Resnick, Benjamin Booker
- Episode 163 : Louis C.K., a performance from the Broadway cast of Rocky
- Episode 164 : Don Rickles, Carmen Lynch, the Ghost of a Saber Tooth Tiger
- Episode 165 : Shailene Woodley, Peyton Manning
- Episode 166 : Jon Cryer, Elizabeth Olsen, Foster the People
- Episode 167 : Mariah Carey, Rick Harrison
- Episode 168 : James Franco, Idina Menzel, a performance by the Broadway cast of 'If/Then'
- Episode 169 : Nathan Fillion, Tom Dreesen, Hunter Hayes
- Episode 170 : Harry Connick Jr., Jesse Eisenberg, the Black Keys
- Episode 171 : Jim Parsons, Julie Chen, Hozier
- Episode 172 : Barbara Walters, Elle Fanning, Randy Houser
- Episode 173 : Adam Sandler, Thomas Haden Church
- Episode 174 : Lea Michele, Andy Kindler, Chromeo
- Episode 175 : Jack Hanna, Stephen Malkmus & the Jicks
- Episode 176 : Kid scientists, Sarah Silverman, We Are Scientists
- Episode 177 : Sgt. Kyle J. White, Judy Greer, Dierks Bentley
- Episode 178 : Donald Trump, Indianapolis 500 winner Ryan Hunter-Reay, Elizabeth Cook
- Episode 179 : Martin Short, John Oliver, Spanish Gold
- Episode 180 : Anderson Cooper, Victor Espinoza, the Afghan Whigs
- Episode 181 : Hugh Jackman, Joe List, Elvis Costello
- Episode 182 : Kelsey Grammer, Willie Nelson
- Episode 183 : Dave Chappelle, Laura Prepon, a Top Ten List presented by Miss USA, the Orwells
- Episode 184 : Christopher Walken, Janelle Monae
- Episode 185 : Regis Philbin, Paul Morrissey, First Aid Kit
- Episode 117 :
- Episode 118 : Johnny Galecki, Andre Benjamin, Delta Spirit
- Episode 119 : Mariska Hargitay, Simon Amstell, Kandace Springs
- Episode 120 : Aziz Ansari, Tom Dreesen
- Episode 121 : Robert Downey Jr., Sarah Paulson, Lizzo
- Episode 122 : Anderson Cooper, Gina Rodriguez, Hatsune Miku
- Episode 123 : Robert Duvall, Elle Fanning, Rival Sons
- Episode 124 : Chelsea Handler; Keegan-Michael Key and Jordan Peele; Angaleena Presley
- Episode 125 : Russell Brand, Dave Grohl, Foo Fighters
- Episode 126 : Michael Keaton, Foo Fighters
- Episode 127 : Bill Murray, Foo Fighters
- Episode 128 : Tom Selleck, Jenny Slate, Foo Fighters
- Episode 129 : Jessica Chastain, Lenny Marcus, Foo Fighters
- Episode 130 : Amy Poehler, Sen. Jeff Flake, Sen. Martin Heinrich, Mastodon, Jerry Lee Lewis
- Episode 131 : Taylor Swift, Tom Mison
- Episode 132 : Jim Carrey, David Tennant
- Episode 133 : Brian Williams, Perfume Genius
- Episode 134 : Keith Olbermann, Brian Regan, Run the Jewels
- Episode 135 : Martin Short, Father John Misty
- Episode 136 : Jennifer Lopez, Rob Riggle, Kimbra
- Episode 137 : Whoopi Goldberg, Jimmy Page, Mapei
- Episode 138 : Amy Schumer, Jeff Caldwell
- Episode 139 : Katie Holmes, Alex Zanardi
- Episode 140 : Steve Carell, Martha Stewart, OK Go
- Episode 141 : Jennifer Lawrence, Boris Johnson
- Episode 142 : Jon Stewart, Shawn Mendes
- Episode 143 : Kristin Chenoweth; Chris Young
- Episode 144 : Jason Sudeikis, Allison Janney, Damien Rice
- Episode 145 : Stupid Pet Tricks, Charlie Day, Hiss Golden Messenger
- Episode 146 : Regis Philbin, Hundred Waters
- Episode 147 : Edward Norton, Jessye Norman
- Episode 148 : Norman Lear, TV on the Radio
- Episode 149 : Seth Rogen, Amy Sedaris
- Episode 150 : Emily Blunt, Adam Resnick, Wu-Tang Clan
- Episode 151 : Jake Gyllenhaal, Dr. John P. Holdren, Nico & Vinz
- Episode 152 : Joaquin Phoenix, Cristela Alonzo, Al Green
- Episode 153 : Ben Stiller, Olivia Munn, LaLa Brooks
- Episode 154 : Meryl Streep, Rebel Wilson, J. Cole
- Episode 155 : Chris Rock, Sting
- Episode 156 : Jamie Foxx, Robert Klein, Dan Penn
- Episode 157 : Emma Stone Top, Marcus Mariota, Bob Seger
- Episode 158 : New Holiday Toys, Anna Kendrick, Charli XCX
- Episode 159 : Tom Brokaw, Will Nelson & Billy Joe Shaver
- Episode 160 : Rosie O’Donnel,l Jeff Altman
- Episode 161 : Jay Thomas, Josh Brolin, Darlene Love
- Episode 162 : Kathy Griffin, David Oyelowo, Lera Lynn
- Episode 163 : Ethan Hawke, Allison Williams, Parquet Courts
- Episode 164 : Julianne Moore, Catfish & the Bottlemen
- Episode 165 : Donald Trump, Chelsea Peretti, Foxygen
- Episode 166 : Michael Somerville, Nicole Atkins
- Episode 167 : Gordon Ramsay, Adam Devine, St. Paul and the Broken Bones
- Episode 168 : Anderson Cooper, Shovels & Rope
- Episode 169 : Amanda Peet, Ryn Weaver
- Episode 170 : Larry David, Dan Patrick, Sleater-Kinney
- Episode 171 : Urban Meyer, Johnny Beehner, Ella Henderson
- Episode 172 : Louis CK, Nicolle Wallace, the Lone Bellow
- Episode 173 : Andrew Luck, Oscar Isaac, Drenge
- Episode 174 : Viola Davis, Ben Schwartz, Marty Stuart
- Episode 175 : John Oliver, Mayim Bialik, Death Cab for Cutie
- Episode 176 : Aziz Ansari, Brian Kiley, Ben Howard
- Episode 177 : Jack Hanna, Sharon Jones and the Dap-Kings
- Episode 178 : Dr. Phil McGraw, Robin Tunney, Diana Krall
- Episode 179 : Ryan Reynolds, Dierks Bentley
- Episode 180 : Martin Short, Bettye Lavette
- Episode 181 : Sienna Miller, Andy Kindler, Bob Mould
- Episode 182 : Steve Carell, Dr. Cornel West
- Episode 183 : Courtney Love, Chris Elliott, Rhiannon Giddens
- Episode 184 : Bill Belichick, Elisabeth Moss, Madisen Ward and the Mama Bear
- Episode 85 : Tom Hanks, Sturgill Simpson
- Episode 86 : Bill Hader, Pat McGann, Shakey Graves
- Episode 87 : Matthew Perry, Adam Scott, Kishi Bashi
- Episode 88 : Dakota Johnson, David Tochinskiy, Twin Shadow
- Episode 89 : Will Smith, Grizfolk
- Episode 90 : Don Cheadle, Ilana Glazer & Abbi Jacobson, Mikky Ekko
- Episode 91 : Kid Scientists, Sean Hayes, Judah & the Lion
- Episode 92 : Helen Mirren, the 2015 Daytona 500 winner, Steve Earle
- Episode 93 : Matthew Broderick, Ellie Kemper, JD McPherson
- Episode 94 : Julianna Margulies, Eric Ripert, Glass Animals
- Episode 95 : Kevin Spacey, Lily James, Alabama Shakes
- Episode 96 : Patricia Arquette, Will Butler
- Episode 97 : Kelsey Grammer, Stevie Wonder
- Episode 98 : Lena Dunham, Bobby Cannavale, Andy Kim with Kevin Drew
- Episode 99 : Kevin Bacon, Jimmie Walker, Airborne Toxic Event
- Episode 100 : Shailene Woodley, Dr. Cornel West, Matthew E. White
- Episode 101 : Will Ferrell, Glen Hansard
- Episode 102 : Norm MacDonald, Theo James
- Episode 103 : Ben Stiller, Tove Lo
- Episode 104 : Bill O'Reilly, Aubrey Plaza
- Episode 105 : James Franco, Jake Johannsen, Action Bronson
- Episode 106 : Neil Patrick Harris, Charlie Cox, the Suffers
- Episode 107 : David Duchovny, Josh Gad, Houndmouth
- Episode 108 : Sen. Al Franken, Billy Eichner, David Sanborn
- Episode 109 : Kelly Ripa, Aasif Mandvi, Fat White Family
- Episode 110 : Mike Myers, Nick Griffin, Banks
- Episode 111 : Sarah Jessica Parker, Julie Chen, Asleep at the Wheel
- Episode 112 : Billy Crystal, Chris Russo, Chris Stapleton
- Episode 113 : Michael J. Fox, Iron & Wine, Ben Bridwell
- Episode 114 : Kevin James, Tom Dreesen, Tracy Chapman
- Episode 115 : Alec Baldwin, John Mayer
- Episode 116 : John Travolta, Amy Schumer, the Waterboys
- Episode 117 : Piedmont Bird Callers, Paul Rudd
- Episode 118 : Bruce Willis, Dawes
- Episode 119 : Robert Downey Jr., Chris Russo, Elvis Costello
- Episode 120 : Jerry Seinfeld, Jason Isbell & Amanda Shires
- Episode 121 : Scarlett Johansson, John Mellencamp, Todd Rundgren
- Episode 122 : Michael Keaton, Future Islands
- Episode 123 : Jack Hanna, John Popper
- Episode 124 : First Lady Michelle Obama Hootie and the Blowfish
- Episode 125 : Steve Martin, Emmylou Harris, Rodney Crowell, Amos Lee, Ralph Stanley, Mark O'Connor
- Episode 126 : President Barack Obama, Will Ferrell, the Avett Brothers, Brandi Carlile
- Episode 127 : Reese Witherspoon, Nathan Lane, Mumford & Sons
- Episode 128 : Martin Short, Norah Jones
- Episode 129 : Tina Fey, First Aid Kit
- Episode 130 : Ray Romano, Brian Regan, Dave Matthews Band
- Episode 131 : Howard Stern, Don Rickles
- Episode 132 : Bill Clinton, Adam Sandler
- Episode 133 : Julia Roberts, Paul Shaffer, Ryan Adams
- Episode 134 : Al Pacino, George Clooney, Tom Waits
- Episode 135 : Oprah Winfrey, Norm Macdonald
- Episode 136 : Tom Hanks, Eddie Vedder
- Episode 137 : Bill Murray, Bob Dylan
- Episode 138 : The Final Late Show with David Letterman
- Episode 149 : Episode 149
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