Grey's Anatomy Season 5, Episode 22 : What a Difference a Day Makes

Grey's Anatomy Season 5, Episode 22 : What a Difference a Day Makes

Izzie has another brain tumor, which leads Derek and Meredith to give their wedding to Izzie and Alex who get married instead. Guest Stars: Jessica Capshaw, Mac Brandt, Candice Afia, Jeffrey Dean Morgan, Payton Silver, Molly Kidder, Joe Williamson, Winston Story, Amrapali Ambegaokar, Tymberlee Hill, Shi Ne Nielson, Mark Saul, Wayne Lopez, Tim Chiou, Amy Gumenick, Roberto Urbina, Robin Gwynne, Trent Gill, Mickey Maxwell,

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